Faculty Profiles

Barbara R. Shaw
William T. Miller Professor Emeritus of Chemistry
Office: 
1105 French Family Science Ctr, Box 90346, Chemistry Department, Durham, NC 27708-0346
Phone: 
(919) 451-9197
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., University of Washington 1973

M.S., University of Washington 1967

B.A., Bryn Mawr College 1965

He, K., et al. “Synthesis of diuridine 3',5'-boranophosphate: H-phosphonate approach.” Tetrahedron Letters, vol. 40, no. 25, June 1999, pp. 4601–04. Scopus, doi:10.1016/S0040-4039(99)00742-X. Full Text

Rait, V., et al. “Boranophosphate nucleic acids--a versatile DNA backbone..” Nucleosides & Nucleotides, vol. 18, no. 6–7, June 1999, pp. 1379–80. Epmc, doi:10.1080/07328319908044721. Full Text

He, K., et al. “Synthesis of 5-substituted 2'-deoxycytidine 5'-(alpha-P-borano)triphosphates, their incorporationinto DNA and effects on exonuclease..” Nucleic Acids Research, vol. 27, no. 8, Apr. 1999, pp. 1788–94. Epmc, doi:10.1093/nar/27.8.1788. Full Text

Sergueeva, Z. A., et al. “Synthesis of dithymidine boranophosphates via stereospecific boronation of H-phosphonate diesters and assignment of their configuration.” Tetrahedron Letters, vol. 40, no. 11, Mar. 1999, pp. 2041–44. Scopus, doi:10.1016/S0040-4039(99)00088-X. Full Text

Rait, V. K., and B. R. Shaw. “Boranophosphates support the RNase H cleavage of polyribonucleotides..” Antisense & Nucleic Acid Drug Development, vol. 9, no. 1, Feb. 1999, pp. 53–60. Epmc, doi:10.1089/oli.1.1999.9.53. Full Text

He, Kaizhang, et al. “Synthesis and Separation of Diastereomers of Ribonucleoside 5'-(alpha-P-Borano)triphosphates..” The Journal of Organic Chemistry, vol. 63, no. 17, Aug. 1998, pp. 5769–73. Epmc, doi:10.1021/jo972002g. Full Text

Krzyzanowska, B. K., et al. “A convenient synthesis of 2'-deoxyribonucleoside 5'-(α-P- borano)triphosphates.” Tetrahedron, vol. 54, no. 20, May 1998, pp. 5119–28. Scopus, doi:10.1016/S0040-4020(98)00251-8. Full Text

Sergueev, D. S., and B. Ramsay Shaw. “H-Phosphate Approach for Solid-Phase Synthesis of Boranophosphate Oligodeoxyribonucleotides and their Characterization.” J. Amer. Chem. Soc., vol. 120, no. 37, 1998, pp. 9417–27.

Hasan, A., et al. “Studies on base-boronated oligonucleotides. 2 (1). Incompatibility of DMT and cyanoborane groups during oligonucleotide synthesis..” Bioconjugate Chemistry, vol. 8, no. 6, Nov. 1997, pp. 813–18. Epmc, doi:10.1021/bc9701205. Full Text

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