Faculty Profiles

Barbara R. Shaw
William T. Miller Distinguished Professor Emeritus of Chemistry
Office: 
1105 French Family Science Ctr, Box 90346, Chemistry Department, Durham, NC 27708-0346
Phone: 
(919) 451-9197
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., University of Washington 1973

M.S., University of Washington 1967

B.A., Bryn Mawr College 1965

He, K., and B. R. Shaw. “Synthesis and separation of diastereomers of uridine 2',3'-cyclic boranophosphate.Bioorganic & Medicinal Chemistry Letters, vol. 11, no. 5, Mar. 2001, pp. 615–17. Epmc, doi:10.1016/s0960-894x(00)00700-9. Full Text

Lin, J., and B. R. Shaw. “Synthesis of a novel triphosphate analogue: Nucleoside α-P-borano, α-P-thiotriphosphate.” Chemical Communications, no. 21, Nov. 2000, pp. 2115–16. Scopus, doi:10.1039/b005059h. Full Text

Lin, J., and B. R. Shaw. “Synthesis of a boron analogue of glucose-conjugated nucleoside diphosphate: Nucleoside α-P-boranodiphosphoglucose.” Tetrahedron Letters, vol. 41, no. 35, Aug. 2000, pp. 6701–04. Scopus, doi:10.1016/S0040-4039(00)01141-2. Full Text

Astriab-Fisher, A., et al. “Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates.Biochemical Pharmacology, vol. 60, no. 1, July 2000, pp. 83–90. Epmc, doi:10.1016/s0006-2952(00)00310-5. Full Text

Sergueeva, Z. A., et al. “Individual isomers of dinucleoside boranophosphates as synthons for incorporation into oligonucleotides: Synthesis and configurational assignment.” Helvetica Chimica Acta, vol. 83, no. 7, Jan. 2000, pp. 1377–91. Scopus, doi:10.1002/1522-2675(20000705)83:7<1377::AID-HLCA1377>3.0.CO;2-S. Full Text

Lin, J., et al. “Synthesis of boron-containing ADP and GDP analogues: Nucleoside 5'-(Pα- boranodiphosphates).” Helvetica Chimica Acta, vol. 83, no. 7, Jan. 2000, pp. 1392–97. Scopus, doi:10.1002/1522-2675(20000705)83:7<1392::AID-HLCA1392>3.0.CO;2-H. Full Text

Sergueeva, Z. A., et al. “Rapid and Selective Reduction of Amide Group by Borane-Amine Complexes in Acyl Protected Nucleosides.” Nuclosides and Nucleotides, vol. 19, no. 1&2, 2000, pp. 275–82.

Ramsay Shaw, B., et al. “Boronated Nucleic Acid Mimics: Antisense and DNA Chip Applications.” Antisense and Nucleic Acid Drug Development, vol. 10, 2000, pp. 131–32.

Lin, J., and B. R. Shaw. “Synthesis and properties of a novel phosphodiester analogue, nucleoside boranophosphorothioate.” Chemical Communications, no. 16, Aug. 1999, pp. 1517–18. Scopus, doi:10.1039/a901157i. Full Text

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