Faculty Profiles

Barbara R. Shaw
William T. Miller Professor Emeritus of Chemistry
Office: 
1105 French Family Science Ctr, Box 90346, Chemistry Department, Durham, NC 27708-0346
Phone: 
(919) 451-9197
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., University of Washington 1973

M.S., University of Washington 1967

B.A., Bryn Mawr College 1965

Xu, Zhihong, and Barbara Ramsay Shaw. “Synthesis, Hydrolysis, and Protonation-Promoted Intramolecular Reductive Breakdown of Potential NRTIs: Stavudine α-P-Borano-γ-P-N-l-tryptophanyltriphosphates..” Molecules (Basel, Switzerland), vol. 20, no. 10, Jan. 2015, pp. 18808–26. Epmc, doi:10.3390/molecules201018808. Full Text

Shaw, Barbara Ramsay. “Versatility of borane nucleic acids mimics for coding, decoding and modulating genetic information..” Nucleic Acids Symposium Series (2004), no. 51, Jan. 2007. Epmc, doi:10.1093/nass/nrm059. Full Text

Li, Ping, and Barbara Ramsay Shaw. “Synthesis of nucleoside boranophosphoramidate prodrugs conjugated with amino acids..” The Journal of Organic Chemistry, vol. 70, no. 6, Mar. 2005, pp. 2171–83. Epmc, doi:10.1021/jo0481248. Full Text

Wan, Jing, and Barbara Ramsay Shaw. “Incorporation of ribonucleoside 5'-(alpha-P-borano)triphosphates into a 20-mer RNA by T7 RNA polymerase..” Nucleosides, Nucleotides & Nucleic Acids, vol. 24, no. 5–7, Jan. 2005, pp. 943–46. Epmc, doi:10.1081/ncn-200059303. Full Text

Khan, Shoeb I., et al. “Synthesis of 5-ethynyl-2'-deoxyuridine-5'-boranomono phosphate as a potential thymidylate synthase inhibitor..” Nucleosides, Nucleotides & Nucleic Acids, vol. 24, no. 5–7, Jan. 2005, pp. 1047–49. Epmc, doi:10.1081/ncn-200060046. Full Text

Wang, Joy Xin, and Barbara Ramsay Shaw. “Synthesis of 5-(1-propynyl)-2'-deoxyuridine 5'-(alpha-P-borano)triphosphate and kinetic characterization as a substrate for mmlv reverse transcriptase..” Nucleosides, Nucleotides & Nucleic Acids, vol. 24, no. 5–7, Jan. 2005, pp. 947–50. Epmc, doi:10.1081/ncn-200059307. Full Text

Wang, Joy Xin, et al. “The effect of a single boranophosphate substitution with defined configuration on the thermal stability and conformation of a DNA duplex..” Nucleosides, Nucleotides & Nucleic Acids, vol. 24, no. 5–7, Jan. 2005, pp. 951–55. Epmc, doi:10.1081/ncn-200059310. Full Text

Dobrikov, Mikhail I., and Barbara Ramsay Shaw. “Affinity of (alpha-P-borano)-NTP analogs to rabbit muscle pyruvate kinase..” Nucleosides, Nucleotides & Nucleic Acids, vol. 24, no. 5–7, Jan. 2005, pp. 983–87. Epmc, doi:10.1081/ncn-200059378. Full Text

Li, Ping, and Barbara Ramsay Shaw. “Model synthesis of nucleoside boranophosphoramidate with amino acid for prodrug purpose..” Nucleosides, Nucleotides & Nucleic Acids, vol. 24, no. 5–7, Jan. 2005, pp. 675–78. Epmc, doi:10.1081/ncn-200060244. Full Text

Li, Ping, and Barbara Ramsay Shaw. “"Convenient Synthesis of Nucleoside Borane Diphosphate Analogues: Deoxy-and Ribonucleoside 5'-P -Boranodiphosphates".” J. Organic Chem., vol. 69, no. 2, 2004, pp. 7051–57.

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