Faculty Profiles

Ashutosh Chilkoti
Professor in the Department of Chemistry
1427 CIEMAS, Durham, NC 27708
(919) 660-5373
+1 919 660 5409



Ph.D., University of Washington 1991

Joh, DY, Hucknall, AM, Wei, Q, Mason, KA, Lund, ML, Fontes, CM, Hill, RT, Blair, R, Zimmers, Z, Achar, RK, Tseng, D, Gordan, R, Freemark, M, Ozcan, A, and Chilkoti, A. "Inkjet-printed point-of-care immunoassay on a nanoscale polymer brush enables subpicomolar detection of analytes in blood." Proceedings of the National Academy of Sciences of the United States of America 114.34 (August 7, 2017): E7054-E7062. Full Text

Wang, J, Bhattacharyya, J, Mastria, E, and Chilkoti, A. "A quantitative study of the intracellular fate of pH-responsive doxorubicin-polypeptide nanoparticles." Journal of Controlled Release : Official Journal of the Controlled Release Society 260 (August 2017): 100-110. Full Text

Weitzhandler, I, Dzuricky, M, Hoffmann, I, Garcia Quiroz, F, Gradzielski, M, and Chilkoti, A. "Micellar Self-Assembly of Recombinant Resilin-/Elastin-Like Block Copolypeptides." Biomacromolecules 18.8 (August 2017): 2419-2426. Full Text

Bhattacharyya, J, Ren, X-R, Mook, RA, Wang, J, Spasojevic, I, Premont, RT, Li, X, Chilkoti, A, and Chen, W. "Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth." Nanoscale 9.34 (August 2017): 12709-12717. Full Text

Tang, L, Navarro, LA, Chilkoti, A, and Zauscher, S. "High-Molecular-Weight Polynucleotides by Transferase-Catalyzed Living Chain-Growth Polycondensation." Angewandte Chemie (International Ed. in English) 56.24 (June 2017): 6778-6782. Full Text

MacEwan, SR, and Chilkoti, A. "From Composition to Cure: A Systems Engineering Approach to Anticancer Drug Carriers." Angewandte Chemie (International Ed. in English) 56.24 (June 2017): 6712-6733. (Review) Full Text

Simon, JR, Carroll, NJ, Rubinstein, M, Chilkoti, A, and López, GP. "Programming molecular self-assembly of intrinsically disordered proteins containing sequences of low complexity." Nature Chemistry 9.6 (June 2017): 509-515. Full Text

Han, W, Chilkoti, A, and López, GP. "Self-assembled hybrid elastin-like polypeptide/silica nanoparticles enable triggered drug release." Nanoscale 9.18 (May 2017): 6178-6186. Full Text

Weinberger, A, Walter, V, MacEwan, SR, Schmatko, T, Muller, P, Schroder, AP, Chilkoti, A, and Marques, CM. "Cargo self-assembly rescues affinity of cell-penetrating peptides to lipid membranes." Scientific Reports 7 (March 6, 2017). Full Text

Bhattacharyya, J, Weitzhandler, I, Ho, SB, McDaniel, JR, Li, X, Tang, L, Liu, J, Dewhirst, M, and Chilkoti, A. "Encapsulating a Hydrophilic Chemotherapeutic into Rod-like Nanoparticles of a Genetically Encoded Asymmetric Triblock Polypeptide Improves its Efficacy." Advanced Functional Materials 27.12 (March 2017). Full Text


Liu, W, Dreher, MR, Chow, DC, Zalutsky, MR, and Chilkoti, A. "Tracking the in vivo fate of recombinant polypeptides by isotopic labeling." 3rd International Nanomedicine and Drug Delivery Symposium. September 26, 2005 - September 27, 2005. Baltimore, MD.: ELSEVIER SCIENCE BV, August 28, 2006. Full Text

Wong, JY, Plant, AL, Schmidt, CE, Shea, L, Coury, AJ, Chen, CS, Barron, AE, Klok, HA, Deming, TJ, Saltzman, WM, Chilkoti, A, Luo, D, and Uhrich, K. "Materials Research Society Symposium Proceedings: Preface." December 1, 2004.

Valiaev, A, Lim, DW, Clark, R, Chilkoti, A, and Zauscher, S. "Mechanics of stimulus-responsive elastin-like polypeptides studied by force spectroscopy." Meeting of the Division of Chemical Toxicology of the American-Chemical-Society held at the 228th National Meeting of the American-Chemical-Society. August 22, 2004 - August 26, 2004. Philadelphia, PA.: AMER CHEMICAL SOC, August 22, 2004.

Prohaska, S, Dreher, M, Dewhirst, MW, Chilkoti, A, Pries, AR, Westerhoff, M, and Cornelissen, AJM. "3-D reconstruction of tumor vascular networks." 2004.