Faculty Profiles

Ashutosh Chilkoti
Professor in the Department of Chemistry
Office: 
1427 CIEMAS, Durham, NC 27708
Phone: 
(919) 660-5373
Fax: 
+1 919 660 5409

Overview

Education:

Ph.D., University of Washington 1991

Varanko, AK, and Chilkoti, A. "Molecular and Materials Engineering for Delivery of Peptide Drugs to Treat Type 2 Diabetes." Advanced Healthcare Materials (February 14, 2019): e1801509-null. (Review) Full Text

Yousefpour, P, Ahn, L, Tewksbury, J, Saha, S, Costa, SA, Bellucci, JJ, Li, X, and Chilkoti, A. "Conjugate of Doxorubicin to Albumin-Binding Peptide Outperforms Aldoxorubicin." Small (Weinheim an Der Bergstrasse, Germany) (February 13, 2019): e1804452-null. Full Text

Fontes, CM, Achar, RK, Joh, DY, Ozer, I, Bhattacharjee, S, Hucknall, A, and Chilkoti, A. "Engineering the Surface Properties of a Zwitterionic Polymer Brush to Enable the Simple Fabrication of Inkjet-Printed Point-of-Care Immunoassays." Langmuir : the Acs Journal of Surfaces and Colloids 35.5 (February 2019): 1379-1390. Full Text

Banskota, S, Yousefpour, P, Kirmani, N, Li, X, and Chilkoti, A. "Long circulating genetically encoded intrinsically disordered zwitterionic polypeptides for drug delivery." Biomaterials 192 (February 2019): 475-485. Full Text

Mozhdehi, D, Luginbuhl, KM, Dzuricky, M, Costa, SA, Xiong, S, Huang, FC, Lewis, MM, Zelenetz, SR, Colby, CD, and Chilkoti, A. "Genetically Encoded Cholesterol-Modified Polypeptides." Journal of the American Chemical Society (January 4, 2019). Full Text

Costa, S, Mozhdehi, D, Dzuricky, M, Isaacs, FJ, Brustad, E, and Chilkoti, A. "Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bioorthogonally Conjugated Drug." Nano Letters (December 12, 2018). Full Text

Roberts, S, Harmon, TS, Schaal, JL, Miao, V, Li, KJ, Hunt, A, Wen, Y, Oas, TG, Collier, JH, Pappu, RV, and Chilkoti, A. "Injectable tissue integrating networks from recombinant polypeptides with tunable order." Nature Materials 17.12 (December 2018): 1154-1163. Full Text

Roberts, S, Harmon, TS, Schaal, JL, Miao, V, Li, KJ, Hunt, A, Wen, Y, Oas, TG, Collier, JH, Pappu, RV, and Chilkoti, A. "Author Correction: Injectable tissue integrating networks from recombinant polypeptides with tunable order." Nature Materials 17.12 (December 2018): 1164-null. Full Text

Yousefpour, P, McDaniel, JR, Prasad, V, Ahn, L, Li, X, Subrahmanyan, R, Weitzhandler, I, Suter, S, and Chilkoti, A. "Genetically Encoding Albumin Binding into Chemotherapeutic-loaded Polypeptide Nanoparticles Enhances Their Antitumor Efficacy." Nano Letters (November 21, 2018). Full Text

Ruff, KM, Roberts, S, Chilkoti, A, and Pappu, RV. "Advances in Understanding Stimulus-Responsive Phase Behavior of Intrinsically Disordered Protein Polymers." Journal of Molecular Biology 430.23 (November 2018): 4619-4635. (Review) Full Text

Pages

Bhattacharyya, J, Bellucci, JJ, and Chilkoti, A. "Elastin-Like Polypeptides: Bio-Inspired Smart Polymers for Protein Purification, Drug Delivery and Tissue Engineering." Biomaterials from Nature for Advanced Devices and Therapies. January 1, 2016. 106-126. Full Text

Hill, RT, and Chilkoti, A. "Surface Patterning." Biomaterials Science: An Introduction to Materials: Third Edition. January 1, 2013. 276-301. Full Text

Nusz, G, and Chilkoti, A. "Individual plasmonic nanostructures as label free biosensors." Nanoplasmonic Sensors. January 1, 2012. 105-126. Full Text

Bhattacharyya, J, and Chilkoti, A. "Abstract 4481: Genetically encoded chimeric polypeptide nanoparticles for gemcitabine delivery to solid tumors.": American Association for Cancer Research (AACR), October 1, 2014. Full Text

Liu, W, Mukerji, R, Li, X, Schaal, J, Bhattacharyya, J, Zalutsky, M, and Chilkoti, A. "Abstract 4583: In situ photocontrolled intratumoral depot for combined photodynamic therapy and brachytherapy for solid tumor.": American Association for Cancer Research (AACR), October 1, 2014. Full Text

Quiroz, FG, and Chilkoti, A. "The language of protein polymers." January 1, 2014. Full Text

Garanger, E, Mac Ewan, S, Brulet, A, Bataille, L, Sandre, O, Chilkoti, A, and Lecommandoux, S. "Elastin-based amphiphilic copolymers as precision building blocks for controlled self-assembly." September 8, 2013.

Tang, L, Tjong, V, Gu, R, Chilkoti, A, and Zauscher, S. "Enzyme catalyzed polymerization of DNA amphiphiles that self-assemble into star-like micelles." September 8, 2013.

Weinberger, A, Macewan, S, Schmatko, T, Schroder, A, Chilkoti, A, and Marques, CM. "Interactions of elastin-like polypeptides with model membranes on GUVs." July 2013.

Pages