Faculty Profiles

Ashutosh Chilkoti
Professor in the Department of Chemistry
Office: 
1427 CIEMAS, Durham, NC 27708
Phone: 
(919) 660-5373
Fax: 
+1 919 660 5409

Overview

Education:

Ph.D., University of Washington 1991

Li, L, Li, NK, Tu, Q, Im, O, Mo, C-K, Han, W, Fuss, WH, Carroll, NJ, Chilkoti, A, Yingling, YG, Zauscher, S, and López, GP. "Functional Modification of Silica through Enhanced Adsorption of Elastin-Like Polypeptide Block Copolymers." Biomacromolecules 19.2 (February 2018): 298-306. Full Text

Mastria, EM, Cai, LY, Kan, MJ, Li, X, Schaal, JL, Fiering, S, Gunn, MD, Dewhirst, MW, Nair, SK, and Chilkoti, A. "Nanoparticle formulation improves doxorubicin efficacy by enhancing host antitumor immunity." Journal of Controlled Release : Official Journal of the Controlled Release Society 269 (January 2018): 364-373. Full Text

Luginbuhl, KM, Mozhdehi, D, Dzuricky, M, Yousefpour, P, Huang, FC, Mayne, NR, Buehne, KL, and Chilkoti, A. "Recombinant Synthesis of Hybrid Lipid-Peptide Polymer Fusions that Self-Assemble and Encapsulate Hydrophobic Drugs." Angewandte Chemie (International ed. in English) 56.45 (November 2017): 13979-13984. Full Text

Wang, J, Dzuricky, M, and Chilkoti, A. "The Weak Link: Optimization of the Ligand-Nanoparticle Interface To Enhance Cancer Cell Targeting by Polymer Micelles." Nano Letters 17.10 (October 2017): 5995-6005. Full Text

Joh, DY, Hucknall, AM, Wei, Q, Mason, KA, Lund, ML, Fontes, CM, Hill, RT, Blair, R, Zimmers, Z, Achar, RK, Tseng, D, Gordan, R, Freemark, M, Ozcan, A, and Chilkoti, A. "Inkjet-printed point-of-care immunoassay on a nanoscale polymer brush enables subpicomolar detection of analytes in blood." Proceedings of the National Academy of Sciences of the United States of America 114.34 (August 7, 2017): E7054-E7062. Full Text

Bhattacharyya, J, Ren, X-R, Mook, RA, Wang, J, Spasojevic, I, Premont, RT, Li, X, Chilkoti, A, and Chen, W. "Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth." Nanoscale 9.34 (August 2017): 12709-12717. Full Text

Wang, J, Bhattacharyya, J, Mastria, E, and Chilkoti, A. "A quantitative study of the intracellular fate of pH-responsive doxorubicin-polypeptide nanoparticles." Journal of Controlled Release : Official Journal of the Controlled Release Society 260 (August 2017): 100-110. Full Text

Weitzhandler, I, Dzuricky, M, Hoffmann, I, Garcia Quiroz, F, Gradzielski, M, and Chilkoti, A. "Micellar Self-Assembly of Recombinant Resilin-/Elastin-Like Block Copolypeptides." Biomacromolecules 18.8 (August 2017): 2419-2426. Full Text

Tang, L, Navarro, LA, Chilkoti, A, and Zauscher, S. "High-Molecular-Weight Polynucleotides by Transferase-Catalyzed Living Chain-Growth Polycondensation." Angewandte Chemie (International Ed. in English) 56.24 (June 2017): 6778-6782. Full Text

MacEwan, SR, and Chilkoti, A. "From Composition to Cure: A Systems Engineering Approach to Anticancer Drug Carriers." Angewandte Chemie (International Ed. in English) 56.24 (June 2017): 6712-6733. (Review) Full Text

Pages

Liu, W, McDaniel, JR, Li, X, Schaal, J, Bhattacharyya, J, Zalutsky, MR, and Chilkoti, A. "Abstract 4341: A novel injectable polymer liquid that self-assembles into radioactive “seeds” for brachytherapy." April 15, 2013. Full Text

Caudill, C, Bhattacharyya, J, and Chilkoti, A. "Delivery of paclitaxel with elastin-like polypeptides." April 7, 2013.

Sinclair, SM, Bhattacharyya, J, Little, D, Bowles, RD, Gooden, DM, Toone, EJ, Chilkoti, A, and Setton, LA. "PHARMACOKINETICS OF A THERMALLY RESPONSIVE CURCUMIN CONJUGATE FOR LOCAL ANTAGONISM OF NEUROINFLAMMATION IN DISC HERNIATION." April 2013. Full Text

Ferris, R, Hucknall, A, Kwon, BS, Chilkoti, A, and Zauscher, S. "Field-induced nanolithography for the patterning of non-fouling polymer brushes." March 25, 2012.

Fluegel, S, Kiefer, T, Heimann, N, Buehler, J, Fischer, K, McDaniel, J, Chilkoti, A, and Schmidt, M. "Conjugates of polypeptides and synthetic polymers with oligonucleotides: Stars, micelles and multiblockcopolymers." March 25, 2012.

Pages