Faculty Profiles

Ashutosh Chilkoti
Professor in the Department of Chemistry
Office: 
1427 CIEMAS, Durham, NC 27708
Phone: 
(919) 660-5373
Fax: 
+1 919 660 5409

Overview

Education:

Ph.D., University of Washington 1991

Costa, S, Mozhdehi, D, Dzuricky, M, Isaacs, FJ, Brustad, E, and Chilkoti, A. "Active Targeting of Cancer Cells by Nanobody Decorated Polypeptide Micelle with Bioorthogonally Conjugated Drug." Nano Letters (December 12, 2018). Full Text

Roberts, S, Harmon, TS, Schaal, JL, Miao, V, Li, KJ, Hunt, A, Wen, Y, Oas, TG, Collier, JH, Pappu, RV, and Chilkoti, A. "Injectable tissue integrating networks from recombinant polypeptides with tunable order." Nature Materials 17.12 (December 2018): 1154-1163. Full Text

Roberts, S, Harmon, TS, Schaal, JL, Miao, V, Li, KJ, Hunt, A, Wen, Y, Oas, TG, Collier, JH, Pappu, RV, and Chilkoti, A. "Author Correction: Injectable tissue integrating networks from recombinant polypeptides with tunable order." Nature Materials 17.12 (December 2018): 1164-null. Full Text

Banskota, S, Yousefpour, P, Kirmani, N, Li, X, and Chilkoti, A. "Long circulating genetically encoded intrinsically disordered zwitterionic polypeptides for drug delivery." Biomaterials 192 (November 28, 2018): 475-485. Full Text

Yousefpour, P, McDaniel, JR, Prasad, V, Ahn, L, Li, X, Subrahmanyan, R, Weitzhandler, I, Suter, S, and Chilkoti, A. "Genetically Encoding Albumin Binding into Chemotherapeutic-loaded Polypeptide Nanoparticles Enhances Their Antitumor Efficacy." Nano Letters (November 21, 2018). Full Text

Ruff, KM, Roberts, S, Chilkoti, A, and Pappu, RV. "Advances in Understanding Stimulus-Responsive Phase Behavior of Intrinsically Disordered Protein Polymers." Journal of Molecular Biology 430.23 (November 2018): 4619-4635. (Review) Full Text

Fontes, CM, Achar, RK, Joh, DY, Ozer, I, Bhattacharjee, S, Hucknall, A, and Chilkoti, A. "Engineering the Surface Properties of a Zwitterionic Polymer Brush to Enable the Simple Fabrication of Inkjet-Printed Point-of-Care Immunoassays." Langmuir : the Acs Journal of Surfaces and Colloids (August 21, 2018). Full Text

Gu, R, Oweida, T, Yingling, YG, Chilkoti, A, and Zauscher, S. "Enzymatic Synthesis of Nucleobase-Modified Single-Stranded DNA Offers Tunable Resistance to Nuclease Degradation." Biomacromolecules 19.8 (August 2018): 3525-3535. Full Text

Li, NK, Roberts, S, Quiroz, FG, Chilkoti, A, and Yingling, YG. "Sequence Directionality Dramatically Affects LCST Behavior of Elastin-Like Polypeptides." Biomacromolecules 19.7 (July 2018): 2496-2505. Full Text

Mozhdehi, D, Luginbuhl, KM, Simon, JR, Dzuricky, M, Berger, R, Varol, HS, Huang, FC, Buehne, KL, Mayne, NR, Weitzhandler, I, Bonn, M, Parekh, SH, and Chilkoti, A. "Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature-triggered hierarchical self-assembly." Nature Chemistry 10.5 (May 2018): 496-505. Full Text

Pages

Hill, RT, and Chilkoti, A. "Surface Patterning." Biomaterials Science.: Elsevier. 2013. 276-301. Full Text

Nusz, G, and Chilkoti, A. "Individual Plasmonic Nanostructures as Label Free Biosensors." Nanoplasmonic Sensors.: Springer New York. 2012. 105-126. Full Text

Bhattacharyya, J, Bellucci, JJ, and Chilkoti, A. "Elastin-Like Polypeptides: Bio-Inspired Smart Polymers for Protein Purification, Drug Delivery and Tissue Engineering(Published online)." Biomaterials from Nature for Advanced Devices and Therapies.: John Wiley & Sons, Inc... 106-126. Full Text

Bhattacharyya, J, and Chilkoti, A. "Abstract 4481: Genetically encoded chimeric polypeptide nanoparticles for gemcitabine delivery to solid tumors.": American Association for Cancer Research (AACR), October 1, 2014. Full Text

Liu, W, Mukerji, R, Li, X, Schaal, J, Bhattacharyya, J, Zalutsky, M, and Chilkoti, A. "Abstract 4583: In situ photocontrolled intratumoral depot for combined photodynamic therapy and brachytherapy for solid tumor.": American Association for Cancer Research (AACR), October 1, 2014. Full Text

Quiroz, FG, and Chilkoti, A. "The language of protein polymers." January 1, 2014. Full Text

Tang, L, Tjong, V, Gu, R, Chilkoti, A, and Zauscher, S. "Enzyme catalyzed polymerization of DNA amphiphiles that self-assemble into star-like micelles." September 8, 2013.

Garanger, E, Mac Ewan, S, Brulet, A, Bataille, L, Sandre, O, Chilkoti, A, and Lecommandoux, S. "Elastin-based amphiphilic copolymers as precision building blocks for controlled self-assembly." September 8, 2013.

Weinberger, A, Macewan, S, Schmatko, T, Schroder, A, Chilkoti, A, and Marques, CM. "Interactions of elastin-like polypeptides with model membranes on GUVs." July 2013.

Pages