
NIH Postdoctoral Fellow, Chemistry, California Institute of Technology 2010 - 2013
Ph.D., University of Texas, Austin 2010
B.S., Trinity University 2004
Zafferani, Martina, et al. “Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures.” Biorxiv, Dec. 2020. Pubmed, doi:10.1101/2020.12.05.409821. Full Text
Hargrove, Amanda E. “Small molecule-RNA targeting: starting with the fundamentals.” Chemical Communications (Cambridge, England), vol. 56, no. 94, Nov. 2020, pp. 14744–56. Epmc, doi:10.1039/d0cc06796b. Full Text
Davila-Calderon, Jesse, et al. “IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex.” Nature Communications, vol. 11, no. 1, Sept. 2020, p. 4775. Epmc, doi:10.1038/s41467-020-18594-3. Full Text
Donlic, Anita, et al. “Regulation of MALAT1 triple helix stability and in vitro degradation by diphenylfurans.” Nucleic Acids Research, vol. 48, no. 14, Aug. 2020, pp. 7653–64. Epmc, doi:10.1093/nar/gkaa585. Full Text
Padroni, G., et al. “Systematic analysis of the interactions driving small molecule-RNA recognition.” Rsc Medicinal Chemistry, vol. 11, no. 7, July 2020, pp. 802–13. Scopus, doi:10.1039/d0md00167h. Full Text
Umuhire Juru, Aline, et al. “Template-guided selection of RNA ligands using imine-based dynamic combinatorial chemistry.” Chemical Communications (Cambridge, England), vol. 56, no. 24, Mar. 2020, pp. 3555–58. Epmc, doi:10.1039/d0cc00266f. Full Text
Ganser, Laura R., et al. “Demonstration that Small Molecules can Bind and Stabilize Low-abundance Short-lived RNA Excited Conformational States.” J Mol Biol, vol. 432, no. 4, Feb. 2020, pp. 1297–304. Pubmed, doi:10.1016/j.jmb.2019.12.009. Full Text
Hargrove, Amanda E. “The next 20 years of Medicinal Research Reviews.” Medicinal Research Reviews, vol. 40, no. 1, Jan. 2020, pp. 7–8. Epmc, doi:10.1002/med.21656. Full Text
Morgan, Brittany S., et al. “R-BIND: An Interactive Database for Exploring and Developing RNA-Targeted Chemical Probes.” Acs Chemical Biology, vol. 14, no. 12, Dec. 2019, pp. 2691–700. Epmc, doi:10.1021/acschembio.9b00631. Full Text
Patwardhan, Neeraj N., et al. “Driving factors in amiloride recognition of HIV RNA targets.” Organic & Biomolecular Chemistry, vol. 17, no. 42, Oct. 2019, pp. 9313–20. Epmc, doi:10.1039/c9ob01702j. Full Text
Padroni, Giacomo, et al. Differentiation and classification of RNA motifs using small molecule-based pattern recognition. Vol. 623, 2019, pp. 101–30. Epmc, doi:10.1016/bs.mie.2019.05.022. Full Text
Hargrove, Amanda E. Preface. Vol. 623, 2019, pp. xv–xvii. Pubmed, doi:10.1016/S0076-6879(19)30266-6. Full Text
Hargrove, Amanda E. “RNA Recognition.” RNA RECOGNITION, edited by A. E. Hargrove, vol. 623, ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD, 2019, pp. XV–XVII.
Umuhire Juru, Aline, and Amanda E. Hargrove. “Frameworks for targeting RNA with small molecules.” The Journal of Biological Chemistry, 2020. Epmc, doi:10.1074/jbc.rev120.015203. Full Text