Faculty Profiles

Amanda Hargrove
Associate Professor of Chemistry
3219 French Science Center, Box 90346, Durham, NC 27708
(919) 660-1522
(919) 660-1605



NIH Postdoctoral Fellow, Chemistry, California Institute of Technology 2010 - 2013

Ph.D., University of Texas, Austin 2010

B.S., Trinity University 2004

Research Areas:
Synthesis, Biomolecular Structure and Function, Biological, Organic

Raskatov, Jevgenij A., et al. “Pharmacokinetics of Py-Im polyamides depend on architecture: cyclic versus linear.Journal of the American Chemical Society, vol. 134, no. 18, May 2012, pp. 7995–99. Epmc, doi:10.1021/ja302588v. Full Text

Hargrove, Amanda E., et al. “Artificial receptors for the recognition of phosphorylated molecules.Chemical Reviews, vol. 111, no. 11, Nov. 2011, pp. 6603–782. Epmc, doi:10.1021/cr100242s. Full Text

Hargrove, Amanda E., et al. “Chemical functionalization of oligodeoxynucleotides with multiple boronic acids for the polyvalent binding of saccharides.Bioconjugate Chemistry, vol. 22, no. 3, Mar. 2011, pp. 388–96. Epmc, doi:10.1021/bc100376x. Full Text

Hargrove, Amanda E., et al. “Boronic acid porphyrin receptor for ginsenoside sensing.Organic Letters, vol. 12, no. 21, Nov. 2010, pp. 4804–07. Epmc, doi:10.1021/ol1019647. Full Text

Hargrove, A. E., et al. “Algorithms for the determination of binding constants and enantiomeric excess in complex host: Guest equilibria using optical measurements.” New Journal of Chemistry, vol. 34, no. 2, Jan. 2010, pp. 348–54. Scopus, doi:10.1039/b9nj00498j. Full Text

Collins, B. E., et al. “Probing intramolecular B-N interactions in ortho-aminomethyl arylboronic acids.” Journal of Organic Chemistry, vol. 74, no. 11, June 2009, pp. 4055–60. Scopus, doi:10.1021/jo900187a. Full Text

Pikulski, Michael, et al. “Sequencing and characterization of oligosaccharides using infrared multiphoton dissociation and boronic acid derivatization in a quadrupole ion trap.Journal of the American Society for Mass Spectrometry, vol. 18, no. 12, Dec. 2007, pp. 2094–106. Epmc, doi:10.1016/j.jasms.2007.09.005. Full Text

Spence, J. D., et al. “Porphyrenediynes: synthesis and cyclization of meso-enediynylporphyrins.” Tetrahedron Letters, vol. 48, no. 4, Jan. 2007, pp. 725–28. Scopus, doi:10.1016/j.tetlet.2006.10.164. Full Text

Sessler, J. L., et al. “Chemical and electrochemical oxidation of N-alkyl cyclo[n]-pyrroles.” Journal of Porphyrins and Phthalocyanines, vol. 10, no. 12, Jan. 2006, pp. 1329–36. Scopus, doi:10.1142/S1088424606000703. Full Text

Davila-Calderon, Jesse, et al. Small Molecule Targeting IRES Domain Inhibits Enterovirus 71 Replication via an Allosteric Mechanism that Stabilizes a Ternary Complex. Cold Spring Harbor Laboratory. Crossref, doi:10.1101/2020.03.10.981167. Full Text