Faculty Profiles

Alvin L. Crumbliss
University Distinguished Service Professor Emeritus
2104 French Family Science Center, Box 90346, Durham, NC 27708-0354
(919) 660-1540



Ph.D., Northwestern University 1968

B.A., Knox College 1964

Research Areas:
Biomolecular Structure and Function, Biological, Inorganic

Heymann, Jared J., et al. “Kinetics and mechanism of exogenous anion exchange in FeFbpA-NTA: significance of periplasmic anion lability and anion binding activity of ferric binding protein A.Journal of Biological Inorganic Chemistry, vol. 15, no. 2, Feb. 2010, pp. 237–48. Epmc, doi:10.1007/s00775-009-0589-2. Full Text

Harrington, James M., and Alvin L. Crumbliss. “The redox hypothesis in siderophore-mediated iron uptake.Biometals : An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine, vol. 22, no. 4, Aug. 2009, pp. 679–89. Epmc, doi:10.1007/s10534-009-9233-4. Full Text

Crumbliss, A. L., and J. M. Harrington. “Iron sequestration by small molecules: Thermodynamic and kinetic studies of natural siderophores and synthetic model compounds.” Advances in Inorganic Chemistry, vol. 61, July 2009, pp. 179–250. Scopus, doi:10.1016/S0898-8838(09)00204-9. Full Text

Tristani, E. M., et al. “Characterization of second coordination shell ionophore-siderophore host-guest assemblies and binding selectivities in binary and complex mixtures by electrospray ionization mass spectrometry.” Journal of Inclusion Phenomena and Macrocyclic Chemistry, vol. 64, no. 1–2, June 2009, pp. 57–65. Scopus, doi:10.1007/s10847-009-9536-7. Full Text

Siburt, Claire J. Parker, et al. “Hijacking transferrin bound iron: protein-receptor interactions involved in iron transport in N. gonorrhoeae.Metallomics : Integrated Biometal Science, vol. 1, no. 3, Jan. 2009, pp. 249–55. Epmc, doi:10.1039/b902860a. Full Text

Weaver, Katherine D., et al. “Ga3+ as a mechanistic probe in Fe3+ transport: characterization of Ga3+ interaction with FbpA.Journal of Biological Inorganic Chemistry, vol. 13, no. 6, Aug. 2008, pp. 887–98. Epmc, doi:10.1007/s00775-008-0376-5. Full Text

Flaherty, Meghan M., et al. “An investigation of hemopexin redox properties by spectroelectrochemistry: biological relevance for heme uptake.Biometals : An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine, vol. 21, no. 3, June 2008, pp. 239–48. Epmc, doi:10.1007/s10534-007-9112-9. Full Text

Roulhac, Petra L., et al. “Ex vivo analysis of synergistic anion binding to FbpA in Gram-negative bacteria.Biochemistry, vol. 47, no. 14, Apr. 2008, pp. 4298–305. Epmc, doi:10.1021/bi701188x. Full Text