Faculty Profiles

Alvin L. Crumbliss
University Distinguished Service Professor Emeritus
2104 French Family Science Center, Box 90346, Durham, NC 27708-0354
(919) 660-1540



Ph.D., Northwestern University 1968

B.A., Knox College 1964

Research Areas:
Biomolecular Structure and Function, Biological, Inorganic

Roulhac, PL, Powell, KD, Dhungana, S, Weaver, KD, Mietzner, TA, Crumbliss, AL, and Fitzgerald, MC. "SUPREX (Stability of Unpurified Proteins from Rates of H/D Exchange) analysis of the thermodynamics of synergistic anion binding by ferric-binding protein (FbpA), a bacterial transferrin." Biochemistry 43.50 (December 21, 2004): 15767-15774. Full Text

Bonaventura, C, Fago, A, Henkens, R, and Crumbliss, AL. "Critical redox and allosteric aspects of nitric oxide interactions with hemoglobin." Antioxidants & Redox Signaling 6.6 (December 2004): 979-991. (Review) Full Text

Dhungana, S, Anderson, DS, Mietzner, TA, and Crumbliss, AL. "Phosphate ester hydrolysis is catalyzed by a bacterial transferrin: potential implications for in vivo iron transport mechanisms." J Inorg Biochem 98.11 (November 2004): 1975-1977. Full Text

Bonaventura, C, Crumbliss, AL, and Weber, RE. "New insights into the proton-dependent oxygen affinity of Root effect haemoglobins." Acta Physiol Scand 182.3 (November 2004): 245-258. (Review) Full Text

Dhungana, S, Ratledge, C, and Crumbliss, AL. "Iron chelation properties of an extracellular siderophore exochelin MS." Inorg Chem 43.20 (October 4, 2004): 6274-6283. Full Text

Heymann, JJ, and Crumbliss, AL. "Kinetics and mechanism of axial ligand substitution of alkyl cobaloximes by substituted pyridines in different solvents." Chemtracts 17.10 (October 1, 2004): 527-533. (Review)

Gabricević, M, Anderson, DS, Mietzner, TA, and Crumbliss, AL. "Kinetics and mechanism of iron(III) complexation by ferric binding protein: the role of phosphate." Biochemistry 43.19 (May 18, 2004): 5811-5819. Full Text

Dhungana, S, Taboy, CH, Zak, O, Larvie, M, Crumbliss, AL, and Aisen, P. "Redox properties of human transferrin bound to its receptor." Biochemistry 43.1 (January 13, 2004): 205-209. Full Text

Dhungana, S, White, PS, and Crumbliss, AL. "Crystal and molecular structures of ionophore-siderophore host-guest supramolecular assemblies relevant to molecular recognition." J Am Chem Soc 125.48 (December 3, 2003): 14760-14767. Full Text