Faculty Profiles

Alvin L. Crumbliss
University Distinguished Service Professor Emeritus
Office: 
2104 French Family Science Center, Box 90346, Durham, NC 27708-0354
Phone: 
(919) 660-1540

Overview

Education:

Ph.D., Northwestern University 1968

B.A., Knox College 1964

Research Areas:
Biomolecular Structure and Function, Biological, Inorganic

Fago, A, Crumbliss, AL, Hendrich, MP, Pearce, LL, Peterson, J, Henkens, R, and Bonaventura, C. "Oxygen binding to partially nitrosylated hemoglobin." Biochimica Et Biophysica Acta 1834.9 (September 2013): 1894-1900. Full Text

Romano, Ariel, et al. “Regulation of iron transport related genes by boron in the marine bacterium Marinobacter algicola DG893..” Metallomics : Integrated Biometal Science, vol. 5, no. 8, Aug. 2013, pp. 1025–30. Epmc, doi:10.1039/c3mt00068k. Full Text

Grant, Gerald A., et al. “The 62nd Annual Meeting of the Congress of Neurological Surgeons was held in Chicago, Illinois from October 6-10, 2012. Preface..” Neurosurgery, vol. 60 Suppl 1, Aug. 2013. Epmc, doi:10.1227/neu.0000000000000006. Full Text

Bonaventura, C, Henkens, R, Alayash, AI, Banerjee, S, and Crumbliss, AL. "Molecular controls of the oxygenation and redox reactions of hemoglobin." Antioxidants & Redox Signaling 18.17 (June 2013): 2298-2313. (Review) Full Text

Mollan, TL, Banerjee, S, Wu, G, Parker Siburt, CJ, Tsai, A-L, Olson, JS, Weiss, MJ, Crumbliss, AL, and Alayash, AI. "α-Hemoglobin stabilizing protein (AHSP) markedly decreases the redox potential and reactivity of α-subunits of human HbA with hydrogen peroxide." The Journal of Biological Chemistry 288.6 (February 2013): 4288-4298. Full Text

Fago, A., et al. “Oxygen binding to partially nitrosylated hemoglobin.” Biochimica Et Biophysica Acta  Proteins and Proteomics, vol. 1834, no. 9, 2013, pp. 1894–900. Scival, doi:10.1016/j.bbapap.2013.04.017. Full Text

Harrington, James M., et al. “Characterization of the aqueous iron(III) chelation chemistry of a potential Trojan Horse antimicrobial agent: chelate structure, stability and pH dependent speciation..” Biometals : An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine, vol. 25, no. 5, Oct. 2012, pp. 1023–36. Epmc, doi:10.1007/s10534-012-9568-0. Full Text

Banerjee, S, Jia, Y, Siburt, CJP, Abraham, B, Wood, F, Bonaventura, C, Henkens, R, Crumbliss, AL, and Alayash, AI. "Haptoglobin alters oxygenation and oxidation of hemoglobin and decreases propagation of peroxide-induced oxidative reactions." Free Radical Biology & Medicine 53.6 (September 2012): 1317-1326. Full Text

Harrington, JM, Boyd, WA, Smith, MV, Rice, JR, Freedman, JH, and Crumbliss, AL. "Amelioration of metal-induced toxicity in Caenorhabditis elegans: utility of chelating agents in the bioremediation of metals." Toxicological Sciences : an Official Journal of the Society of Toxicology 129.1 (September 2012): 49-56. Full Text

Kraiter, DC, Wisian-Neilson, P, Zhang, C, and Crumbliss, AL. "Synthesis and redox characterization of phosphazene terpolymers with pendant ferrocene groups." Macromolecules 45.9 (May 8, 2012): 3658-3668. Full Text

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