Faculty Profiles

Alvin L. Crumbliss
Professor Emeritus of Chemistry
2104 French Family Science Center, Box 90346, Durham, NC 27708-0354
(919) 660-1540



Ph.D., Northwestern University 1968

B.A., Knox College 1964

Research Areas:
Biomolecular Structure and Function, Biological, Inorganic

Strader, MB, Bangle, R, Parker Siburt, CJ, Varnado, CL, Soman, J, Benitez Cardenas, AS, Samuel, PP, Singleton, EW, Crumbliss, AL, Olson, JS, and Alayash, AI. "Engineering oxidative stability in human hemoglobin based on the Hb providence (βK82D) mutation and genetic cross-linking." The Biochemical journal 474.24 (December 2017): 4171-4192. Full Text

Gupta, A, Pratt, RD, and Crumbliss, AL. "Ferrous iron content of intravenous iron formulations." Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine 29.3 (June 2016): 411-415. Full Text

Crumbliss, AL, Franz, KJ, and Thiele, DJ. "Preface." BioMetals 28.3 (June 2015): 431-431. Full Text

Crumbliss, AL, Franz, KJ, and Thiele, DJ. "Preface. Biometals 2014--Proceedings of the 9th International Symposium Biometals 2014 at Duke University, Durham, NC, USA." Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine 28.3 (June 2015): 431-null. Full Text

Banerjee, S, Weerasinghe, AJ, Parker Siburt, CJ, Kreulen, RT, Armstrong, SK, Brickman, TJ, Lambert, LA, and Crumbliss, AL. "Bordetella pertussis FbpA binds both unchelated iron and iron siderophore complexes." Biochemistry 53.24 (June 13, 2014): 3952-3960. Full Text

Mollan, TL, Jia, Y, Banerjee, S, Wu, G, Kreulen, RT, Tsai, A-L, Olson, JS, Crumbliss, AL, and Alayash, AI. "Redox properties of human hemoglobin in complex with fractionated dimeric and polymeric human haptoglobin." Free Radical Biology & Medicine 69 (April 2014): 265-277. Full Text

Miller, EP, Böttger, LH, Weerasinghe, AJ, Crumbliss, AL, Matzanke, BF, Meyer-Klaucke, W, Küpper, FC, and Carrano, CJ. "Surface-bound iron: a metal ion buffer in the marine brown alga Ectocarpus siliculosus?." J Exp Bot 65.2 (February 2014): 585-594. Full Text

Weerasinghe, AJ, Amin, SA, Barker, RA, Othman, T, Romano, AN, Parker Siburt, CJ, Tisnado, J, Lambert, LA, Huxford, T, Carrano, CJ, and Crumbliss, AL. "Borate as a synergistic anion for Marinobacter algicola ferric binding protein, FbpA: a role for boron in iron transport in marine life." J Am Chem Soc 135.39 (October 2, 2013): 14504-14507. Full Text

Fago, A, Crumbliss, AL, Hendrich, MP, Pearce, LL, Peterson, J, Henkens, R, and Bonaventura, C. "Oxygen binding to partially nitrosylated hemoglobin." Biochimica Et Biophysica Acta 1834.9 (September 2013): 1894-1900. Full Text


Crumbliss, AL. "Aqueous solution equilibrium and kinetic studies of iron siderophore and model siderophore complexes." Handbook of Microbial Iron Chelates (1991). January 1, 2017. 177-234. Full Text

Crumbliss, AL, Henkens, RW, Perine, SC, Tubergen, KR, Kitchell, BS, and Stonehuerner, J. "Amperometric glucose sensor fabricated from glucose oxidase and a mediator coimmobilized on a colloidal gold hydrogel electrode." January 1, 2017. Full Text