Total Synthesis of Neurologically Active Terpenoid Natural Products
Professor Timothy Newhouse (Yale University, Department of Chemistry)
Host: Professor Jennifer Roizen
Wednesday, February 14, 2018 - 1:30pm to 3:00pm
Location: French Family Science Center 4233
Rosenthal, Janet

Link for Professor Newhouse

Abstract:  This talk will describe the total synthesis of neurologically active terpenoid natural products using novel strategies and methodologies for step-efficient syntheses.  Methodological developments in the area of allyl-palladium catalysis will be described in detail that have allowed for alpha, beta-dehydrogenation of a variety of carbonyl compounds.  Unique strategies and key retrosynthetic disconnections are guided by computational investigation.