Rational Design of Antibiotics for Tuberculosis and Development of New Chemistry for Antibiotic Synthesis
Professor Courtney Aldrich (University of Minnesota, Department of Medicinal Chemistry)
Host: Professor Emily Derbyshire
Tuesday, March 6, 2018 - 11:40am to 1:10pm
Location: French Family Science Center 2237
Rosenthal, Janet

Link for Professor Aldrich

Abstract:  The design, synthesis, and biological characterization of a new class of antibiotics which target siderophore biosynthesis will be described.  This work also led to the development of novel methodology for recycling phosphines in the Mitsunobu, Wittig, Appel, and Staudinger reactions that has proven useful for synthesis of the reported antibiotics.