Faculty Profiles

Ashutosh Chilkoti
Professor in the Department of Chemistry
Office: 
1427 CIEMAS, Durham, NC 27708
Phone: 
(919) 660-5373
Fax: 
+1 919 660 5409

Overview

Education:

Ph.D., University of Washington 1991

Gu, R, Oweida, T, Yingling, YG, Chilkoti, A, and Zauscher, S. "Enzymatic synthesis of nucleobase-modified single-stranded DNA offers tunable resistance to nuclease degradation." Biomacromolecules (July 16, 2018). Full Text

Li, NK, Roberts, S, Quiroz, FG, Chilkoti, A, and Yingling, YG. "Sequence Directionality Dramatically Affects LCST Behavior of Elastin-Like Polypeptides." Biomacromolecules 19.7 (July 2018): 2496-2505. Full Text

Ruff, KM, Roberts, S, Chilkoti, A, and Pappu, RV. "Advances in Understanding Stimulus Responsive Phase Behavior of Intrinsically Disordered Protein Polymers." Journal of Molecular Biology (June 24, 2018). (Review) Full Text

Mozhdehi, D, Luginbuhl, KM, Simon, JR, Dzuricky, M, Berger, R, Varol, HS, Huang, FC, Buehne, KL, Mayne, NR, Weitzhandler, I, Bonn, M, Parekh, SH, and Chilkoti, A. "Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature-triggered hierarchical self-assembly." Nature Chemistry 10.5 (May 2018): 496-505. Full Text

Gilroy, CA, Roberts, S, and Chilkoti, A. "Fusion of fibroblast growth factor 21 to a thermally responsive biopolymer forms an injectable depot with sustained anti-diabetic action." Journal of Controlled Release : Official Journal of the Controlled Release Society 277 (May 2018): 154-164. Full Text

Dzuricky, M, Roberts, S, and Chilkoti, A. "Convergence of Artificial Protein Polymers and Intrinsically Disordered Proteins." Biochemistry 57.17 (May 2018): 2405-2414. Full Text

Costa, SA, Simon, JR, Amiram, M, Tang, L, Zauscher, S, Brustad, EM, Isaacs, FJ, and Chilkoti, A. "Photo-Crosslinkable Unnatural Amino Acids Enable Facile Synthesis of Thermoresponsive Nano- to Microgels of Intrinsically Disordered Polypeptides." Advanced materials (Deerfield Beach, Fla.) 30.5 (February 2018). Full Text

Li, L, Li, NK, Tu, Q, Im, O, Mo, C-K, Han, W, Fuss, WH, Carroll, NJ, Chilkoti, A, Yingling, YG, Zauscher, S, and López, GP. "Functional Modification of Silica through Enhanced Adsorption of Elastin-Like Polypeptide Block Copolymers." Biomacromolecules 19.2 (February 2018): 298-306. Full Text

Mastria, EM, Cai, LY, Kan, MJ, Li, X, Schaal, JL, Fiering, S, Gunn, MD, Dewhirst, MW, Nair, SK, and Chilkoti, A. "Nanoparticle formulation improves doxorubicin efficacy by enhancing host antitumor immunity." Journal of Controlled Release : Official Journal of the Controlled Release Society 269 (January 2018): 364-373. Full Text

Luginbuhl, KM, Mozhdehi, D, Dzuricky, M, Yousefpour, P, Huang, FC, Mayne, NR, Buehne, KL, and Chilkoti, A. "Recombinant Synthesis of Hybrid Lipid-Peptide Polymer Fusions that Self-Assemble and Encapsulate Hydrophobic Drugs." Angewandte Chemie (International ed. in English) 56.45 (November 2017): 13979-13984. Full Text

Pages

Bhattacharyya, J, Bellucci, JJ, and Chilkoti, A. "Elastin-Like Polypeptides: Bio-Inspired Smart Polymers for Protein Purification, Drug Delivery and Tissue Engineering." Biomaterials from Nature for Advanced Devices and Therapies. January 1, 2016. 106-126. Full Text

Hill, RT, and Chilkoti, A. "Surface Patterning." Biomaterials Science: An Introduction to Materials: Third Edition. January 1, 2013. 276-301. Full Text

Nusz, G, and Chilkoti, A. "Individual plasmonic nanostructures as label free biosensors." Nanoplasmonic Sensors. January 1, 2012. 105-126. Full Text

Liu, W, Mukerji, R, Li, X, Schaal, J, Bhattacharyya, J, Zalutsky, M, and Chilkoti, A. "Abstract 4583: In situ photocontrolled intratumoral depot for combined photodynamic therapy and brachytherapy for solid tumor." October 1, 2014. Full Text

Quiroz, FG, and Chilkoti, A. "The language of protein polymers." January 1, 2014. Full Text

Tang, L, Tjong, V, Gu, R, Chilkoti, A, and Zauscher, S. "Enzyme catalyzed polymerization of DNA amphiphiles that self-assemble into star-like micelles." September 8, 2013.

Garanger, E, Mac Ewan, S, Brulet, A, Bataille, L, Sandre, O, Chilkoti, A, and Lecommandoux, S. "Elastin-based amphiphilic copolymers as precision building blocks for controlled self-assembly." September 8, 2013.

Weinberger, A, Macewan, S, Schmatko, T, Schroder, A, Chilkoti, A, and Marques, CM. "Interactions of elastin-like polypeptides with model membranes on GUVs." July 2013.

Pages