Our work focuses on the design and application of novel pulsed techniques, using controlled radiation fields to alter dynamics. The heart of the work is chemical physics, and most of what we do is ultrafast laser spectroscopy or nuclear magnetic resonance, but the focus is on solving problems of societal importance. For example, we developed technologies to tailor laser pulses and pulse trains, and use them to look at a skin mole to see if it is cancerous (or how likely it is to become metastatic), or to do three-dimensional images of Renaissance paintings to infer artist's intent. We extended fundamental quantum mechanics and radiofrequency pulse sequence design to create nuclear spin states that are protected from their environment, and use these states to improve magnetic resonance imaging. We pioneered new methods to detect macroscopic coherences in bulk matter, between spins separated by hundreds of microns, and use these coherences to image temperature in hyperthermic cancer therapy or improve obesity diagnosis without ionizing radiation. All of these highly interdisciplinary projects involve an intimate mixture of theory and experiment, and they often include a broad range of collaborators with complementary expertise.