Hargrove Group

Publications

Current Work

Patwardhan, N. N.; Ganser, L. R.; Kapral, G. J.; Eubanks, C. S.; Lee, J.; Sathyamoorthy, B.; Al-Hashimi, H. M.; Hargrove, A. E. "Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR."  MedChemComm 2017, DOI: 10.1039/C6MD00729E
 

Eubanks, C.S.; Forte, J.E.; Kapral, G. J.; Hargrove, A.E. "Small Molecule-Based Pattern Recognition to Classify RNA Structure." Journal of the American Chemical Society. 2017, 139, 409-416. DOI: 10.1021/jacs.6b11087.

McFadden, E.J.; Hargrove, A.E. "Biochemical Methods To Investigate lncRNA and the Influence of lncRNA:Protein Complexes on Chromatin." Biochemistry2016, 55, 1615-1630. DOI: 10.1021/acs.biochem.5b01141.
 

Morgan, B.S.; Hargrove, A.E. "Chapter 7 Synthetic Receptors for Oligonucleotides and Nucleic Acids." In Synthetic Receptors for Biomolecules: Design Principles and Applications; Smith, B.D., Ed.; The Royal Society of Chemistry: Cambridge, 2015, p 253. DOI: 10.1039/9781782622062-00253

Burg, J.M.; Link, J.E.; Morgan, B.S.; Heller, F.J.; Hargrove, A.E.; McCafferty, D.G. "KDM1 Class Flavin-Dependent Protein Lysine Demethylases." Biopolymers. 2015104, 213-246.  DOI: 10.1002/bip.22643

Previous Work

Hargrove, A.E.; Martinez, T.F.; Hare, A.A.; Kurmis, A.A.; Philips, J.W.; Sud, S.; Pienta, K.J.; Dervan, P.B. "Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide."PLoS One, 2015, 10, 11.

Nickols, N. G.; Szablowski, J. O.; Hargrove, A. E.; Li, B. C.; Raskatov, J. A.; Dervan, P. B. "Activity of a Py-Im polyamide targeted to the estrogen response element." Molecular Cancer Therapeutics, 2013, 12, 675-684.

Jevgenij A. Raskatov, Nickolas G. Nickols, Amanda E. Hargrove, Georgi Marinov, Barbara Wold and Peter B. Dervan. “Gene Expression Changes in a Tumor Xenograft by a Py-Im Polyamide.” Proceedings of the National Academy of Sciences. 2012, 109, 16041-16045.

Hargrove, Amanda E.; Raskatov, Jevgenij A.; Meier, Jordan L.; Montgomery, David C.; Dervan, Peter B. “Characterization and solubilization of pyrrole-imidazole polyamide aggregates.” Journal of Medicinal Chemistry. 2012, 55, 5425-5432.

Raskatov, Jevgenij A.; Hargrove, Amanda E.; So, Alex Y.; Dervan, Peter B. “Pharmacokinetics of Py-Im Polyamides Depend on Architecture: Cyclic versus Linear.” Journal of the American Chemical Society. 2012, 134(18), 7995-7999.

Hargrove, Amanda E.; Nieto, Sonia; Zhang, Tianzhi; Sessler, Jonathan L.; Anslyn, Eric V. “Artificial receptors for the recognition of phosphorylated molecules.” Chemical Reviews. 2011, 111(11), 6603-6782.

Hargrove, Amanda E.; Ellington, Andrew D.; Anslyn, Eric V.; Sessler, Jonathan L. “Chemical functionalization of oligodeoxynucleotides with multiple boronic acids for the polyvalent binding of saccharides.” Bioconjugate Chemistry. 2011, 22, 388-396.

Hargrove, Amanda E.; Reyes, Ryan N.; Riddington, Ian; Anslyn, Eric V.; Sessler, Jonathan L. “Boronic acid porphyrin receptor for ginsenoside sensing.” Organic Letters. 2010, 12(21), 4804-4807.

Hargrove, Amanda E.; Zhong, Zhenlin; Shabbir, Shagufta H.; Sessler, Jonathan L., Anslyn, Eric V. “Algorithms for the determination of binding constants and enantiomeric excess in complex host:guest equilibria using optical measurements.” New Journal of Chemistry. 2010, 34, 348-354

Collins, Byron E.; Sorey, Steven; Hargrove, Amanda E.; Shabbir, Shagufta H.; Lynch, Vincent M.; Anslyn, Eric V.  “Probing intramolecular B-N interactions in protic media.” Journal of Organic Chemistry, 2009, 74(11), 4055 - 4066.

Pikulski, Michael; Hargrove, Amanda; Shabbir, Shagufta H.; Anslyn, Eric V.; Brodbelt, Jennifer S. “Sequencing and characterization of oligosaccharides using infrared multiphoton dissociation and boronic acid derivatization in a quadrupole ion trap.”  Journal of the American Society for Mass Spectrometry, 2007, 18, 2094-2106.

Spence, John D.; Hargrove, Amanda E.; Crampton, Hannah L.; Thomas, David W. “Porphyrenediynes: synthesis and cyclization of meso-enediynylporphyrins.” Tetrahedron Letters, 2007, 48(4), 725-728.

Sessler, Jonathan L.; Lee, Jeong Tae; Ou, Zhongping; Köhler, Thomas; Hargrove, Amanda E.; Cho, Won-Seob; Lynch, Vincent; Kadish, Karl M.  “Chemical and electrochemical oxidation of N-alkyl cyclo[n]pyrroles.” Journal of Porphyrins and Phthalocyanines, 2006, 10, 1329-1336.

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