Faculty Profiles

Steven Malcolmson
Assistant Professor of Chemistry
Office: 
1103 French Science Center, Durham, NC 27708
Phone: 
(919) 660-1575
Fax: 
(919) 660-1605

Overview

Education:

Postdoctoral Fellow, Prof. Christopher Walsh, Harvard Medical School 2010 - 2013

Ph.D., Boston College 2010

B.A., Boston University 2004

Research Areas:
Synthesis, Inorganic, Organic

Walsh, CT, Malcolmson, SJ, and Young, TS. "Three ring posttranslational circuses: insertion of oxazoles, thiazoles, and pyridines into protein-derived frameworks." ACS Chem Biol 7.3 (March 16, 2012): 429-442. Full Text

Crawford, JM, Mahlstedt, SA, Malcolmson, SJ, Clardy, J, and Walsh, CT. "Dihydrophenylalanine: a prephenate-derived Photorhabdus luminescens antibiotic and intermediate in dihydrostilbene biosynthesis." Chem Biol 18.9 (September 23, 2011): 1102-1112. Full Text

Zhang, W, Ntai, I, Bolla, ML, Malcolmson, SJ, Kahne, D, Kelleher, NL, and Walsh, CT. "Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics." J Am Chem Soc 133.14 (April 13, 2011): 5240-5243. Full Text

Hoveyda, AH, Malcolmson, SJ, Meek, SJ, and Zhugralin, AR. "Catalytic Enantioselective Olefin Metathesis and Natural Product Synthesis." (June 7, 2010): 343-348. (Chapter) Full Text

Ji, JX, Chan, ASC, Helmchen, G, Kazmaier, U, Förster, S, Ojima, I, Kaloko, JJ, Chaterpaul, SJ, Teng, YHG, Lin, CF, Mikami, K, Aikawa, K, Hoveyda, AH, Malcolmson, SJ, Meek, SJ, and Zhugralin, AR. "Asymmetric Carbon-Carbon Bond-Forming Reactions." (March 26, 2010): 437-770. (Chapter) Full Text

Hoveyda, AH, Malcolmson, SJ, Meek, SJ, and Zhugralin, AR. "Catalytic enantioselective olefin metathesis in natural product synthesis. Chiral metal-based complexes that deliver high enantioselectivity and more." Angew Chem Int Ed Engl 49.1 (2010): 34-44. (Review) Full Text

Meek, SJ, Malcolmson, SJ, Li, B, Schrock, RR, and Hoveyda, AH. "The significance of degenerate processes to enantioselective olefin metathesis reactions promoted by stereogenic-at-Mo complexes." J Am Chem Soc 131.45 (November 18, 2009): 16407-16409. Full Text

Harvey, JS, Malcolmson, SJ, Dunne, KS, Meek, SJ, Thompson, AL, Schrock, RR, Hoveyda, AH, and Gouverneur, V. "Enantioselective synthesis of P-stereogenic phosphinates and phosphine oxides by molybdenum-catalyzed asymmetric ring-closing metathesis." Angew Chem Int Ed Engl 48.4 (2009): 762-766. Full Text

Malcolmson, SJ, Meek, SJ, Sattely, ES, Schrock, RR, and Hoveyda, AH. "Highly efficient molybdenum-based catalysts for enantioselective alkene metathesis." Nature 456.7224 (December 18, 2008): 933-937. Full Text

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