Faculty Profiles

Steven Malcolmson
Assistant Professor of Chemistry
Office: 
1103 French Science Center, Durham, NC 27708
Phone: 
(919) 660-1575
Fax: 
(919) 660-1605

Overview

Education:

Postdoctoral Fellow, Prof. Christopher Walsh, Harvard Medical School 2010 - 2013

Ph.D., Boston College 2010

B.A., Boston University 2004

Research Areas:
Synthesis, Inorganic, Organic

Theis, T, Ortiz, GX, Logan, AWJ, Claytor, KE, Feng, Y, Huhn, WP, Blum, V, Malcolmson, SJ, Chekmenev, EY, Wang, Q, and Warren, WS. "Direct and cost-efficient hyperpolarization of long-lived nuclear spin states on universal (15)N2-diazirine molecular tags." Science Advances 2.3 (March 25, 2016): e1501438-. Full Text Open Access Copy

Malcolmson, SJ, Young, TS, Ruby, JG, Skewes-Cox, P, and Walsh, CT. "The posttranslational modification cascade to the thiopeptide berninamycin generates linear forms and altered macrocyclic scaffolds." Proc Natl Acad Sci U S A 110.21 (May 21, 2013): 8483-8488. Full Text

Lichtscheidl, AG, Ng, VWL, Müller, P, Takase, MK, Schrock, RR, Malcolmson, SJ, Meek, SJ, Li, B, Kiesewetter, ET, and Hoveyda, AH. "Bipyridine Adducts of Molybdenum Imido Alkylidene and Imido Alkylidyne Complexes." Organometallics 31.12 (June 25, 2012): 4558-4564. Full Text

Walsh, CT, Malcolmson, SJ, and Young, TS. "Three ring posttranslational circuses: insertion of oxazoles, thiazoles, and pyridines into protein-derived frameworks." ACS Chem Biol 7.3 (March 16, 2012): 429-442. Full Text

Crawford, JM, Mahlstedt, SA, Malcolmson, SJ, Clardy, J, and Walsh, CT. "Dihydrophenylalanine: a prephenate-derived Photorhabdus luminescens antibiotic and intermediate in dihydrostilbene biosynthesis." Chem Biol 18.9 (September 23, 2011): 1102-1112. Full Text

Zhang, W, Ntai, I, Bolla, ML, Malcolmson, SJ, Kahne, D, Kelleher, NL, and Walsh, CT. "Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics." J Am Chem Soc 133.14 (April 13, 2011): 5240-5243. Full Text

Hoveyda, AH, Malcolmson, SJ, Meek, SJ, and Zhugralin, AR. "Catalytic Enantioselective Olefin Metathesis and Natural Product Synthesis." (June 7, 2010): 343-348. (Chapter) Full Text

Ji, JX, Chan, ASC, Helmchen, G, Kazmaier, U, Förster, S, Ojima, I, Kaloko, JJ, Chaterpaul, SJ, Teng, YHG, Lin, CF, Mikami, K, Aikawa, K, Hoveyda, AH, Malcolmson, SJ, Meek, SJ, and Zhugralin, AR. "Asymmetric Carbon-Carbon Bond-Forming Reactions." (March 26, 2010): 437-770. (Chapter) Full Text

Hoveyda, AH, Malcolmson, SJ, Meek, SJ, and Zhugralin, AR. "Catalytic enantioselective olefin metathesis in natural product synthesis. Chiral metal-based complexes that deliver high enantioselectivity and more." Angew Chem Int Ed Engl 49.1 (2010): 34-44. (Review) Full Text

Meek, SJ, Malcolmson, SJ, Li, B, Schrock, RR, and Hoveyda, AH. "The significance of degenerate processes to enantioselective olefin metathesis reactions promoted by stereogenic-at-Mo complexes." J Am Chem Soc 131.45 (November 18, 2009): 16407-16409. Full Text

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