Faculty Profiles

Robert J. Lefkowitz
James B. Duke Professor of Medicine
Office: 
467 Clin & Res Labs, Durham, NC 27710
Phone: 
(919) 684-2974
Fax: 
(919) 684-8875

Overview

Education:

M.D., Columbia University 1966

Whalen, EJ, Foster, MW, Matsumoto, A, Ozawa, K, Violin, JD, Que, LG, Nelson, CD, Benhar, M, Keys, JR, Rockman, HA, Koch, WJ, Daaka, Y, Lefkowitz, RJ, and Stamler, JS. "Regulation of beta-adrenergic receptor signaling by S-nitrosylation of G-protein-coupled receptor kinase 2." Cell 129.3 (May 4, 2007): 511-522. Full Text

Whalen, EJ, Foster, MW, Matsumoto, A, Ozawa, K, Violin, JD, Que, LG, Nelson, CD, Benhar, M, Keys, JR, Rockman, HA, Koch, WJ, Daaka, Y, Lefkowitz, RJ, and Stamler, JS. "Regulation of beta-adrenergic receptor signaling by S-nitrosylation of G-protein-coupled receptor kinase 2." CELL 129.3 (May 4, 2007): 511-522. Full Text

Lefkowitz, RJ. "Seven transmembrane receptors: something old, something new." Acta Physiol (Oxf) 190.1 (May 2007): 9-19. (Review) Full Text

Girnita, L, Shenoy, SK, Sehat, B, Vasilcanu, R, Vasilcanu, D, Girnita, A, Lefkowitz, RJ, and Larsson, O. "Beta-arrestin and Mdm2 mediate IGF-1 receptor-stimulated ERK activation and cell cycle progression." J Biol Chem 282.15 (April 13, 2007): 11329-11338. Full Text

Lefkowitz, RJ. "Seven transmembrane receptors: a brief personal retrospective." Biochim Biophys Acta 1768.4 (April 2007): 748-755. Full Text

Nelson, CD, Perry, SJ, Regier, DS, Prescott, SM, Topham, MK, and Lefkowitz, RJ. "Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins." Science 315.5812 (February 2, 2007): 663-666. Full Text

DeWire, SM, Ahn, S, Lefkowitz, RJ, and Shenoy, SK. "β-Arrestins and cell signaling." Annual Review of Physiology 69 (2007): 483-510. Full Text

Lefkowitz, R. "Introduction to special section on β-arrestins." Annual Review of Physiology 69 (2007): xi-xii.

DeWire, SM, Ahn, S, Lefkowitz, RJ, and Shenoy, SK. "Beta-arrestins and cell signaling." Annu Rev Physiol 69 (2007): 483-510. (Review) Full Text

Lefkowitz, RJ, Rajagopal, K, and Whalen, EJ. "New roles for beta-arrestins in cell signaling: not just for seven-transmembrane receptors." Mol Cell 24.5 (December 8, 2006): 643-652. (Review) Full Text

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