Faculty Profiles

Pei Zhou
Professor of Biochemistry
Office: 
270 Sands Building, Research Drive, Durham, NC 27710
Phone: 
(919) 668-6409
Fax: 
(919) 684-8885

Overview

Education:

Post-Doct Fellow, Biological Chemistry, Harvard University 1998 - 2001

Ph.D., Harvard University 1998

Coggins, BE, and Zhou, P. "High resolution 4-D spectroscopy with sparse concentric shell sampling and FFT-CLEAN." J Biomol NMR 42.4 (December 2008): 225-239. Full Text

Barb, AW, and Zhou, P. "Mechanism and inhibition of LpxC: an essential zinc-dependent deacetylase of bacterial lipid A synthesis." Curr Pharm Biotechnol 9.1 (February 2008): 9-15. (Review)

Zeng, JM, Tripathy, C, Zhou, P, and Donald, BR. "A HAUSDORFF-BASED NOE ASSIGNMENT ALGORITHM USING PROTEIN BACKBONE DETERMINED FROM RESIDUAL DIPOLAR COUPLINGS AND ROTAMER PATTERNS." Comput Syst Bioinformatics Conf 2008 (2008): 169-181.

Zeng, J, Tripathy, C, Zhou, P, and Donald, BR. "A Hausdorff-based NOE assignment algorithm using protein backbone determined from residual dipolar couplings and rotamer patterns." Comput Syst Bioinformatics Conf 7 (2008): 169-181.

Barb, AW, Jiang, L, Raetz, CRH, and Zhou, P. "Structure of the deacetylase LpxC bound to the antibiotic CHIR-090: Time-dependent inhibition and specificity in ligand binding." Proc Natl Acad Sci U S A 104.47 (November 20, 2007): 18433-18438. Full Text

Pai, M-T, Tzeng, S-R, Kovacs, JJ, Keaton, MA, Li, SS-C, Yao, T-P, and Zhou, P. "Solution structure of the Ubp-M BUZ domain, a highly specific protein module that recognizes the C-terminal tail of free ubiquitin." J Mol Biol 370.2 (July 6, 2007): 290-302. Full Text

Barb, AW, McClerren, AL, Snehelatha, K, Reynolds, CM, Zhou, P, and Raetz, CRH. "Inhibition of lipid A biosynthesis as the primary mechanism of CHIR-090 antibiotic activity in Escherichia coli." Biochemistry 46.12 (March 27, 2007): 3793-3802. Full Text

Bomar, MG, Pai, M-T, Tzeng, S-R, Li, SS-C, and Zhou, P. "Structure of the ubiquitin-binding zinc finger domain of human DNA Y-polymerase eta." EMBO Rep 8.3 (March 2007): 247-251. Full Text

Coggins, BE, and Zhou, P. "Sampling of the NMR time domain along concentric rings." J Magn Reson 184.2 (February 2007): 207-221. Full Text

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