Faculty Profiles

Pei Zhou
Professor of Chemistry
Office: 
270 Sands Building, Research Drive, Durham, NC 27710
Phone: 
(919) 668-6409
Fax: 
(919) 684-8885

Overview

Education:

Post-Doct Fellow, Biological Chemistry, Harvard University 1998 - 2001

Ph.D., Harvard University 1998

Wen, J, Zhou, P, and Wu, J. "Efficient acquisition of high-resolution 4-D diagonal-suppressed methyl-methyl NOESY for large proteins." Journal of Magnetic Resonance 218 (2012): 128-132. Full Text

Zeng, J, Roberts, KE, Zhou, P, and Donald, BR. "A Bayesian approach for determining protein side-chain rotamer conformations using unassigned NOE data." J Comput Biol 18.11 (November 2011): 1661-1679. Full Text

Martin, JW, Yan, AK, Bailey-Kellogg, C, Zhou, P, and Donald, BR. "A geometric arrangement algorithm for structure determination of symmetric protein homo-oligomers from NOEs and RDCs." J Comput Biol 18.11 (November 2011): 1507-1523. Full Text

Moss, ML, Powell, G, Miller, MA, Edwards, L, Qi, B, Sang, Q-XA, De Strooper, B, Tesseur, I, Lichtenthaler, SF, Taverna, M, Zhong, JL, Dingwall, C, Ferdous, T, Schlomann, U, Zhou, P, Griffith, LG, Lauffenburger, DA, Petrovich, R, and Bartsch, JW. "ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein." The Journal of Biological Chemistry 286.47 (November 2011): 40443-40451. Full Text

Zeng, J, Zhou, P, and Donald, BR. "Protein side-chain resonance assignment and NOE assignment using RDC-defined backbones without TOCSY data." J Biomol NMR 50.4 (August 2011): 371-395. Full Text

Nguyen, BD, Cunningham, D, Liang, X, Chen, X, Toone, EJ, Raetz, CRH, Zhou, P, and Valdivia, RH. "Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis." Proc Natl Acad Sci U S A 108.25 (June 21, 2011): 10284-10289. Full Text

Werner-Allen, JW, Lee, C-J, Liu, P, Nicely, NI, Wang, S, Greenleaf, AL, and Zhou, P. "cis-Proline-mediated Ser(P)5 dephosphorylation by the RNA polymerase II C-terminal domain phosphatase Ssu72." The Journal of Biological Chemistry 286.7 (February 2011): 5717-5726. Full Text

Lee, C-J, Liang, X, Chen, X, Zeng, D, Joo, SH, Chung, HS, Barb, AW, Swanson, SM, Nicholas, RA, Li, Y, Toone, EJ, Raetz, CRH, and Zhou, P. "Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design." Chem Biol 18.1 (January 28, 2011): 38-47. Full Text

Liang, X, Lee, C-J, Chen, X, Chung, HS, Zeng, D, Raetz, CRH, Li, Y, Zhou, P, and Toone, EJ. "Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold." Bioorg Med Chem 19.2 (January 15, 2011): 852-860. Full Text

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