Faculty Profiles

Pei Zhou
Professor of Biochemistry
Office: 
270 Sands Building, Research Drive, Durham, NC 27710
Phone: 
(919) 668-6409
Fax: 
(919) 684-8885

Overview

Education:

Post Doct Fellow, Biological Chemistry, Harvard University 1998 - 2001

Ph.D., Harvard University 1998

Young, HE, Donohue, MP, Smirnova, TI, Smirnov, AI, and Zhou, P. "The UDP-diacylglucosamine pyrophosphohydrolase LpxH in lipid A biosynthesis utilizes Mn2+ cluster for catalysis." J Biol Chem 288.38 (September 20, 2013): 26987-27001. Full Text

Liang, X, Lee, C-J, Zhao, J, Toone, EJ, and Zhou, P. "Synthesis, structure, and antibiotic activity of aryl-substituted LpxC inhibitors." J Med Chem 56.17 (September 12, 2013): 6954-6966. Full Text

Chung, BC, Zhao, J, Gillespie, RA, Kwon, D-Y, Guan, Z, Hong, J, Zhou, P, and Lee, S-Y. "Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis." Science 341.6149 (August 30, 2013): 1012-1016. Full Text

Feng, Y, Theis, T, Liang, X, Wang, Q, Zhou, P, and Warren, WS. "Storage of hydrogen spin polarization in long-lived 13C2 singlet order and implications for hyperpolarized magnetic resonance imaging." J Am Chem Soc 135.26 (July 3, 2013): 9632-9635. Full Text

Emptage, RP, Pemble, CW, York, JD, Raetz, CRH, and Zhou, P. "Mechanistic characterization of the tetraacyldisaccharide-1-phosphate 4'-kinase LpxK involved in lipid A biosynthesis." Biochemistry 52.13 (April 2, 2013): 2280-2290. Full Text

Zeng, D, Zhao, J, Chung, HS, Guan, Z, Raetz, CRH, and Zhou, P. "Mutants resistant to LpxC inhibitors by rebalancing cellular homeostasis." J Biol Chem 288.8 (February 22, 2013): 5475-5486. Full Text

Zeng, J, Zhou, P, and Donald, BR. "HASH: a program to accurately predict protein Hα shifts from neighboring backbone shifts." J Biomol NMR 55.1 (January 2013): 105-118. Full Text

Tripathy, C, Yan, AK, Zhou, P, and Donald, BR. "Extracting structural information from residual chemical shift anisotropy: Analytic solutions for peptide plane orientations and applications to determine protein structure." Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 7821 LNBI (2013): 271-284. Full Text

Zeng, J, Zhou, P, and Donald, BR. "Hash: A program to accurately predict protein Hα shifts from neighboring backbone shifts." Journal of Biomolecular NMR 55.1 (2013): 105-118. Full Text

Pages