Faculty Profiles

Pei Zhou
Professor of Biochemistry
270 Sands Building, Research Drive, Durham, NC 27710
(919) 668-6409
(919) 684-8885



Post-Doct Fellow, Biological Chemistry, Harvard University 1998 - 2001

Ph.D., Harvard University 1998

Young, HE, Zhao, J, Barker, JR, Guan, Z, Valdivia, RH, and Zhou, P. "Discovery of the Elusive UDP-Diacylglucosamine Hydrolase in the Lipid A Biosynthetic Pathway in Chlamydia trachomatis." mBio 7.2 (March 22, 2016): e00090-. Full Text Open Access Copy

Lee, C-J, Liang, X, Wu, Q, Najeeb, J, Zhao, J, Gopalaswamy, R, Titecat, M, Sebbane, F, Lemaitre, N, Toone, EJ, and Zhou, P. "Drug design from the cryptic inhibitor envelope." Nature communications 7 (February 25, 2016): 10638-. Full Text Open Access Copy

Deis, LN, Wu, Q, Wang, Y, Qi, Y, Daniels, KG, Zhou, P, and Oas, TG. "Suppression of conformational heterogeneity at a protein-protein interface." Proceedings of the National Academy of Sciences of the United States of America 112.29 (July 8, 2015): 9028-9033. Full Text Open Access Copy

Martin, JW, Zhou, P, and Donald, BR. "Systematic solution to homo-oligomeric structures determined by NMR." Proteins 83.4 (April 2015): 651-661. Full Text

Wojtaszek, JL, Wang, S, Kim, H, Wu, Q, D'Andrea, AD, and Zhou, P. "Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain." Nucleic acids research 42.22 (December 2014): 13997-14005. Full Text Open Access Copy

Emptage, RP, Tonthat, NK, York, JD, Schumacher, MA, and Zhou, P. "Structural basis of lipid binding for the membrane-embedded tetraacyldisaccharide-1-phosphate 4'-kinase LpxK." The Journal of biological chemistry 289.35 (August 2014): 24059-24068. Full Text

Sampson, TR, Napier, BA, Schroeder, MR, Louwen, R, Zhao, J, Chin, C-Y, Ratner, HK, Llewellyn, AC, Jones, CL, Laroui, H, Merlin, D, Zhou, P, Endtz, HP, and Weiss, DS. "A CRISPR-Cas system enhances envelope integrity mediating antibiotic resistance and inflammasome evasion." Proceedings of the National Academy of Sciences of the United States of America 111.30 (July 14, 2014): 11163-11168. Full Text

Lee, C-J, Liang, X, Gopalaswamy, R, Najeeb, J, Ark, ED, Toone, EJ, and Zhou, P. "Structural basis of the promiscuous inhibitor susceptibility of Escherichia coli LpxC." ACS Chem Biol 9.1 (January 17, 2014): 237-246. Full Text

Masoudi, A, Raetz, CRH, Zhou, P, and Pemble, CW. "Chasing acyl carrier protein through a catalytic cycle of lipid A production." Nature 505.7483 (January 16, 2014): 422-426. Full Text