Faculty Profiles

Michael J. Therien
William R. Kenan, Jr. Professor of Chemistry in Trinity College of Arts and Sciences
5330 French Family Science Cen, Durham, NC 27708
(919) 660-1670
(919) 660-1605



NIH Postdoctoral Research Fellow, Chemistry, California Institute of Technology 1987 - 1990

Ph.D., University of California at San Diego 1987

B.S., University of St. Andrews (Scotland) 1982

Research Areas:
Synthesis, Physical, Biomolecular Structure and Function, Inorganic, Organic, Nanoscience and Materials

Polizzi, NF, Wu, Y, Lemmin, T, Maxwell, AM, Zhang, S-Q, Rawson, J, Beratan, DN, Therien, MJ, and DeGrado, WF. "De novo design of a hyperstable non-natural protein-ligand complex with sub-Å accuracy." Nature chemistry 9.12 (December 2017): 1157-1164. Full Text

Bai, Y, Olivier, J-H, Yoo, H, Polizzi, NF, Park, J, Rawson, J, and Therien, MJ. "Molecular Road Map to Tuning Ground State Absorption and Excited State Dynamics of Long-Wavelength Absorbers." Journal of the American Chemical Society 139.46 (November 2017): 16946-16958. Full Text

Bai, Y, Rawson, J, Roget, SA, Olivier, J-H, Lin, J, Zhang, P, Beratan, DN, and Therien, MJ. "Controlling the excited-state dynamics of low band gap, near-infrared absorbers via proquinoidal unit electronic structural modulation." Chemical science 8.9 (September 2017): 5889-5901. Full Text

Hofmann, CL, O'Sullivan, MC, Detappe, A, Yu, Y, Yang, X, Qi, W, Landon, CD, Therien, MJ, Dewhirst, MW, Ghoroghchian, PP, and Palmer, GM. "NIR-emissive PEG-b-TCL micelles for breast tumor imaging and minimally invasive pharmacokinetic analysis." Nanoscale 9.36 (September 2017): 13465-13476. Full Text

Wang, R, Brugh, AM, Rawson, J, Therien, MJ, and Forbes, MDE. "Alkyne-Bridged Multi[Copper(II) Porphyrin] Structures: Nuances of Orbital Symmetry in Long-Range, Through-Bond Mediated, Isotropic Spin Exchange Interactions." Journal of the American Chemical Society 139.29 (July 2017): 9759-9762. Full Text

Jiang, T, Polizzi, NF, Rawson, J, and Therien, MJ. "Engineering High-Potential Photo-oxidants with Panchromatic Absorption." Journal of the American Chemical Society 139.25 (June 14, 2017): 8412-8415. Full Text

Richert, S, Bullard, G, Rawson, J, Angiolillo, PJ, Therien, MJ, and Timmel, CR. "On the Importance of Electronic Symmetry for Triplet State Delocalization." Journal of the American Chemical Society 139.15 (April 2017): 5301-5304. Full Text

Mimun, LC, Ajithkumar, G, Rightsell, C, Langloss, BW, Therien, MJ, and Sardar, DK. "Synthesis and characterization of Na(Gd0.5Lu0.5)F4: Nd3+,a core-shell free multifunctional contrast agent." Journal of alloys and compounds 695 (February 2017): 280-285. Full Text

Han, Q, Bai, Y, Liu, J, Du, K-Z, Li, T, Ji, D, Zhou, Y, Cao, C, Shin, D, Ding, J, Franklin, AD, Glass, JT, Hu, J, Therien, MJ, Liu, J, and Mitzi, DB. "Additive engineering for high-performance room-temperature-processed perovskite absorbers with micron-size grains and microsecond-range carrier lifetimes." Energy Environ. Sci. (2017). Full Text

Nayak, A, Park, J, De Mey, K, Hu, X, Duncan, TV, Beratan, DN, Clays, K, and Therien, MJ. "Large Hyperpolarizabilities at Telecommunication-Relevant Wavelengths in Donor-Acceptor-Donor Nonlinear Optical Chromophores." ACS central science 2.12 (December 16, 2016): 954-966. Full Text Open Access Copy


Park, JK, Fischer, MC, Susumu, K, Therien, MJ, and Warren, WS. "Femtosecond pulse train shaping for accurate two-photon excited fluorescence measurements." January 1, 2014.

Stecher, JT, Stanton, IN, and Therien, MJ. "Enhancement of dominant UV emission in 10 nm gallium-codoped, upconverting nanocrystals." September 8, 2013.

Rawson, J, Stuart, AC, You, W, and Therien, MJ. "Tailoring porphyrin-based electron acceptors for organic photovoltaics." August 19, 2012.

Rawson, J, Angiolillo, PJ, and Therien, MJ. "Exceptional delocalization of electrons in conjugated porphyrin arrays." August 19, 2012.

Von Bargen, CD, MacDermaid, CM, Murrett, CS, Lee, O-S, Therien, MJ, and Saven, JG. "Understanding the helical wrapping of poly(phenylene-ethynylene) polymers about single-walled carbon nanotubes using molecular simulations." August 19, 2012.

Kamat, NP, Liao, Z, Ruble, BK, Griepenburg, J, Moses, LE, Rawson, J, Robbins, GP, Therien, MJ, Hammer, DA, and Dmochowski, IJ. "Photo-responsive polymersomes and oligonucleotide assemblies." March 25, 2012.