Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
3222 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1547
(919) 660-1605



Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Roulhac, PL, Weaver, KD, Adhikari, P, Anderson, DS, DeArmond, PD, Mietzner, TA, Crumbliss, AL, and Fitzgerald, MC. "Ex vivo analysis of synergistic anion binding to FbpA in Gram-negative bacteria." Biochemistry 47.14 (April 8, 2008): 4298-4305. Full Text

Weaver, KD, Heymann, JJ, Mehta, A, Roulhac, PL, Anderson, DS, Nowalk, AJ, Adhikari, P, Mietzner, TA, Fitzgerald, MC, and Crumbliss, AL. "Ga3+ as a mechanistic probe in Fe3+ transport: Characterization of Ga3+ interaction with FbpA." Journal of Biological Inorganic Chemistry 13.6 (2008): 887-898. Full Text

Fitzgerald, MC, Tang, L, and Hopper, ED. "Chapter 6 Thermodynamic Analysis of Protein Folding and Ligand Binding by SUPREX." Comprehensive Analytical Chemistry 52 (2008): 127-149. Full Text

Tang, L, Roulhac, PL, and Fitzgerald, MC. "H/D exchange and mass spectrometry-based method for biophysical analysis of multidomain proteins at the domain level." Anal Chem 79.22 (November 15, 2007): 8728-8739. Full Text

Tang, L, Hopper, ED, Tong, Y, Sadowsky, JD, Peterson, KJ, Gellman, SH, and Fitzgerald, MC. "H/D exchange- and mass spectrometry-based strategy for the thermodynamic analysis of protein-ligand binding." Anal Chem 79.15 (August 1, 2007): 5869-5877. Full Text

Frankel, BA, Tong, Y, Bentley, ML, Fitzgerald, MC, and McCafferty, DG. "Analysis of Active Site Residues in the Staphylococcus aureus Transpeptidase SrtA Mutational." Biochemistry 46 (2007): 7269-7278. (Academic Article)

Williams, JC, Roulhac, PL, Roy, AG, Vallee, RB, Fitzgerald, MC, and Hendrickson, WA. "Structural and thermodynamic characterization of a cytoplasmic dynein light chain-intermediate chain complex." Proceedings of the National Academy of Sciences of the United States of America 104.24 (2007): 10028-10033. Full Text

Frankel, BA, Tong, Y, Bentley, ML, Fitzgerald, MC, and McCafferty, DG. "Mutational analysis of active site residues in the Staphylococcus aureus transpeptidase SrtA." Biochemistry 46.24 (2007): 7269-7278. Full Text

Dai, SY, and Fitzgerald, MC. "A mass spectrometry-based probe of equilibrium intermediates in protein-folding reactions." Biochemistry 45.42 (October 24, 2006): 12890-12897. Full Text