Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
3222 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1547
(919) 660-1605



Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Yang, X, Wang, M, and Fitzgerald, MC. "Direct analysis of backbone-backbone hydrogen bond formation in protein folding transition states." J Mol Biol 363.2 (October 20, 2006): 506-519. Full Text

Yang, X, and Fitzgerald, MC. "Total chemical synthesis of the B1 domain of protein L from Peptostreptococcus magnus." Bioorg Chem 34.3 (June 2006): 131-141. Full Text

Wang, M, Wales, TE, and Fitzgerald, MC. "Conserved thermodynamic contributions of backbone hydrogen bonds in a protein fold." Proc Natl Acad Sci U S A 103.8 (February 21, 2006): 2600-2604. Full Text

Cisneros, GA, Wang, M, Silinski, P, Fitzgerald, MC, and Yang, W. "Theoretical and experimental determination on two substrates turned over by 4-oxalocrotonate tautomerase." J Phys Chem A 110.2 (January 19, 2006): 700-708. Full Text

Tong, Y, Wuebbens, MM, Rajagopalan, KV, and Fitzgerald, MC. "Thermodynamic analysis of subunit interactions in Escherichia coli molybdopterin synthase." Biochemistry 44.7 (February 22, 2005): 2595-2601. Full Text

Dai, SY, Gardner, MW, and Fitzgerald, MC. "Protocol for the thermodynamic analysis of some proteins using an H/D exchange- and mass spectrometry-based technique." Anal Chem 77.2 (January 15, 2005): 693-697. Full Text

Dai, SY, Gardner, MW, and Fitzgerald, MC. "An Improved Protocol for the SUPREX (Stability of Unpurified Proteins from Rates of H/D Exchange) Analysis of Some Proteins." Analytical Chemistry 77 (2005): 693-697. (Academic Article)

Wang, M, Wales, TE, and Fitzgerald, MC. "The Thermodynamics of Backbone-Backbone Hydrogen Bonds are Conserved ina Protein Fold." Proceedings of the National Academy of Sciences, USA (2005). (Academic Article)

Lin, SM, Haney, RP, Campa, MJ, Fitzgerald, MC, and Patz, EF. "Characterising phase variations in MALDI-TOF data and correcting them by peak alignment." Cancer Inform 1 (2005): 32-40. Open Access Copy

Roulhac, PL, Powell, KD, Dhungana, S, Weaver, KD, Mietzner, TA, Crumbliss, AL, and Fitzgerald, MC. "SUPREX (Stability of Unpurified Proteins from Rates of H/D Exchange) analysis of the thermodynamics of synergistic anion binding by ferric-binding protein (FbpA), a bacterial transferrin." Biochemistry 43.50 (December 21, 2004): 15767-15774. Full Text