Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
Office: 
3222 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1547
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Xu, Y, Wallace, MAG, and Fitzgerald, MC. "Thermodynamic Analysis of the Geldanamycin-Hsp90 Interaction in a Whole Cell Lysate Using a Mass Spectrometry-Based Proteomics Approach." Journal of the American Society for Mass Spectrometry 27.10 (October 2016): 1670-1676. Full Text

Geer Wallace, MA, Kwon, D-Y, Weitzel, DH, Lee, C-T, Stephenson, TN, Chi, J-T, Mook, RA, Dewhirst, MW, Hong, J, and Fitzgerald, MC. "Discovery of Manassantin A Protein Targets Using Large-Scale Protein Folding and Stability Measurements." Journal of Proteome Research 15.8 (August 2016): 2688-2696. Full Text

Geer, MA, and Fitzgerald, MC. "Characterization of the Saccharomyces cerevisiae ATP-Interactome using the iTRAQ-SPROX Technique." Journal of the American Society for Mass Spectrometry 27.2 (February 2016): 233-243. Full Text

Kwon, D-Y, Lee, HE, Weitzel, DH, Park, K, Lee, SH, Lee, C-T, Stephenson, TN, Park, H, Fitzgerald, MC, Chi, J-T, Mook, RA, Dewhirst, MW, Lee, YM, and Hong, J. "Synthesis and Biological Evaluation of Manassantin Analogues for Hypoxia-Inducible Factor 1α Inhibition." Journal of medicinal chemistry 58.19 (October 2015): 7659-7671. Full Text

Adhikari, J, West, GM, and Fitzgerald, MC. "Global analysis of protein folding thermodynamics for disease state characterization." Journal of Proteome Research 14.5 (May 2015): 2287-2297. Full Text

Adhikari, J, and Fitzgerald, MC. "SILAC-pulse proteolysis: A mass spectrometry-based method for discovery and cross-validation in proteome-wide studies of ligand binding." Journal of the American Society for Mass Spectrometry 25.12 (December 2014): 2073-2083. Full Text

Xu, Y, Strickland, EC, and Fitzgerald, MC. "Thermodynamic analysis of protein folding and stability using a tryptophan modification protocol." Analytical Chemistry 86.14 (July 2014): 7041-7048. Full Text

Strickland, EC, Geer, MA, Hong, J, and Fitzgerald, MC. "False-positive rate determination of protein target discovery using a covalent modification- and mass spectrometry-based proteomics platform." J Am Soc Mass Spectrom 25.1 (January 2014): 132-140. Full Text

Geer, MA, and Fitzgerald, MC. "Energetics-based methods for protein folding and stability measurements." Annual review of analytical chemistry (Palo Alto, Calif.) 7 (January 2014): 209-228. (Review) Full Text

Pages