Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
Office: 
3222 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1547
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Ma, L, Powell, KD, and Fitzgerald, MC. "A new H/D exchange- and MALDI-based assay for the quantitative analysis of protein-DNA interactions in solution." Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics (2002): 471-472.

Ghaemmaghami, S, Fitzgerald, MC, and Oas, TG. "Quantitative protein stability measurement in living bacteria." Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics (2002): 109-110.

Powell, KD, and Fitzgerald, MC. "Quantitative determination of protein-peptide binding constants using a new, MALDI- and H/D-exchange based technique." Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics (2002): 445-446.

Fitzgerald, MC, Powell, KD, Wang, MZ, Ma, L, Ghaemmaghami, S, and Oas, TG. "A general mass spectrometry-based method for the quantitation of protein-ligand binding interactions in solution." Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics (2002): 395-396.

Silinski, P, Allingham, MJ, and Fitzgerald, MC. "Guanidine-induced equilibrium unfolding of a homo-hexameric enzyme 4-oxalocrotonate tautomerase (4-OT)." Biochemistry 40.14 (April 2001): 4493-4502. Full Text

Moss, JA, Silinski, P, and Fitzgerald, MC. "Mapping tertiary interactions in protein folding reactions: a novel mass spectrometry- and chemical synthesis-based approach." Fresenius J Anal Chem 369.3-4 (February 2001): 252-257.

Wang, MZ, and Fitzgerald, MC. "A solid sample preparation method that reduces signal suppression effects in the MALDI analysis of peptides." Anal Chem 73.3 (February 1, 2001): 625-631.

Powell, KD, and Fitzgerald, MC. "High Sensitivity Measurements of Protein Stability by H/D Exchange and Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass spectrometry." Analytical Chemistry 73.14 (2001): 3300-3304. (Academic Article)

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