Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
3222 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1547
(919) 660-1605



Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Fitzgerald, MC, Laco, GS, Elder, JH, and Kent, SBH. "A continuous fluorometric assay for the feline immunodeficiency virus protease." Analytical Biochemistry 254.2 (1997): 226-230. Full Text

Fitzgerald, MC, Harris, K, Shevlin, CG, and Siuzdak, G. "Direct characterization of solid phase resin-bound molecules by mass spectrometry." Bioorganic and Medicinal Chemistry Letters 6.8 (1996): 979-982. Full Text

Muir, TW, Dawson, PE, Fitzgerald, MC, and Kent, SBH. "Probing the chemical basis of binding activity in an SH3 domain by protein signature analysis." Chemistry and Biology 3.10 (1996): 817-825.

Fitzgerald, MC, and Siuzdak, G. "Biochemical mass spectrometry: Worth the weight?." Chemistry and Biology 3.9 (1996): 707-715. Full Text

Qian, X, Moris Varas, F, Fitzgerald, MC, and Wong, CH. "C2-Symmetrical Tetrahydroxyazepenes as Inhibitors of Glyosidases and HIV/FIV Proteases." Bioorganic & Medicinal Chemistry 4.12 (1996): 2055-2069. (Academic Article)

Fitzgerald, MC, Chernushevich, I, Standing, KG, Whitman, CP, and Kent, SBH. "Probing the oligomeric structure of an enzyme by electrospray ionization time-of-flight mass spectrometry." Proceedings of the National Academy of Sciences of the United States of America 93.14 (1996): 6851-6856. Full Text

Qian, X, Morís-Varas, F, Fitzgerald, MC, and Wong, C-H. "C2-symmetrical tetrahydroxyazepanes as inhibitors of glycosidases and HIV/FIV proteases." Bioorganic and Medicinal Chemistry 4.12 (1996): 2055-2069. Full Text

Zhu, L, Parr, GR, Fitzgerald, MC, Nelson, CM, and Smith, LM. "Oligodeoxynucleotide fragmentation in MALDI/TOF mass spectrometry using 355-nm radiation." Journal of the American Chemical Society 117.22 (1995): 6048-6056. Full Text

Fitzgerald, MC, Chernushevich, I, Standing, KG, Kent, SBH, and Whitman, CP. "Total chemical synthesis and catalytic properties of the enzyme enantiomers L- and D-4-oxalocrotonate tautomerase." Journal of the American Chemical Society 117.45 (1995): 11075-11080. Full Text

Fitzgerald, MC, and Smith, LM. "Mass spectrometry of nucleic acids: The promise of matrix-assisted laser desorption-ionization (MALDI) mass spectrometry." Annual Review of Biophysics and Biomolecular Structure 24 (1995): 117-140.