Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
3222 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1547
(919) 660-1605



Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Laco, GS, Fitzgerald, MC, Morris, GM, Olson, AJ, Kent, SBH, and Elder, JH. "Molecular analysis of the feline immunodeficiency virus protease: Generation of a novel form of the protease by autoproteolysis and construction of cleavage-resistant proteases." Journal of Virology 71.7 (1997): 5505-5511.

Carrasco, MR, Fitzgerald, MC, Oda, Y, and Kent, SBH. "Direct monitoring of organic reactions on polymeric supports." Tetrahedron Letters 38.36 (1997): 6331-6334. Full Text

Fitzgerald, MC, Laco, GS, Elder, JH, and Kent, SBH. "A Continuous Fluorometric Assay for the FIV Protease." Analytical Biochemistry 254.2 (1997): 226-230. (Academic Article)

Jr, WHJ, Czerwinski, RM, Fitzgerald, MC, and Whitman, CP. "Inactivation of 4-oxalocrotonate tautomerase by 2-oxo-3-pentynoate." Biochemistry 36.50 (1997): 15724-15732. Full Text

Winston, RL, and Fitzgerald, MC. "Mass spectrometry as a readout of protein structure and function." Mass Spectrometry Reviews 16.4 (1997): 165-179.

Fitzgerald, MC, Laco, GS, Elder, JH, and Kent, SBH. "A continuous fluorometric assay for the feline immunodeficiency virus protease." Analytical Biochemistry 254.2 (1997): 226-230. Full Text

Muir, TW, Dawson, PE, Fitzgerald, MC, and Kent, SBH. "Protein signature analysis: A practical new approach for studying structure-activity relationships in peptides and proteins." Methods in Enzymology 289 (1997): 545-564. Full Text

Muir, TW, Dawson, PE, Fitzgerald, MC, and Kent, SBH. "Probing the chemical basis of binding activity in an SH3 domain by protein signature analysis." Chemistry and Biology 3.10 (1996): 817-825.

Fitzgerald, MC, and Siuzdak, G. "Biochemical mass spectrometry: Worth the weight?." Chemistry and Biology 3.9 (1996): 707-715. Full Text

Qian, X, Moris Varas, F, Fitzgerald, MC, and Wong, CH. "C2-Symmetrical Tetrahydroxyazepenes as Inhibitors of Glyosidases and HIV/FIV Proteases." Bioorganic & Medicinal Chemistry 4.12 (1996): 2055-2069. (Academic Article)