Faculty Profiles

Michael C. Fitzgerald
Professor of Chemistry
3222 French Science Center, 124 Science Drive, Durham, NC 27708
(919) 660-1547
(919) 660-1605



Ph.D., University of Wisconsin at Madison 1994

B.S., Davidson College 1989

Research Areas:
Biomolecular Structure and Function, Biological, Analytical

Ogburn, RN, Randall, TA, Xu, Y, Roberts, JH, Mebrahtu, B, Karnuta, JM, Rider, SD, Kissling, GE, London, RE, Pomés, A, Arlian, L, Fitzgerald, MC, and Mueller, GA. "Are dust mite allergens more abundant and/or more stable than other Dermatophagoides pteronyssinus proteins?." The Journal of allergy and clinical immunology 139.3 (March 2017): 1030-1032.e1. Full Text

Roberts, JH, Liu, F, Karnuta, JM, and Fitzgerald, MC. "Discovery of Age-Related Protein Folding Stability Differences in the Mouse Brain Proteome." Journal of proteome research 15.12 (December 2016): 4731-4741. Full Text

Liu, F, and Fitzgerald, MC. "Large-Scale Analysis of Breast Cancer-Related Conformational Changes in Proteins Using Limited Proteolysis." Journal of proteome research 15.12 (December 2016): 4666-4674. Full Text

Jin, L, Wang, D, Gooden, DM, Ball, CH, and Fitzgerald, MC. "Targeted Mass Spectrometry-Based Approach for Protein-Ligand Binding Analyses in Complex Biological Mixtures Using a Phenacyl Bromide Modification Strategy." Analytical chemistry 88.22 (November 2016): 10987-10993. Full Text

Xu, Y, Wallace, MAG, and Fitzgerald, MC. "Thermodynamic Analysis of the Geldanamycin-Hsp90 Interaction in a Whole Cell Lysate Using a Mass Spectrometry-Based Proteomics Approach." Journal of the American Society for Mass Spectrometry 27.10 (October 2016): 1670-1676. Full Text

Geer Wallace, MA, Kwon, D-Y, Weitzel, DH, Lee, C-T, Stephenson, TN, Chi, J-T, Mook, RA, Dewhirst, MW, Hong, J, and Fitzgerald, MC. "Discovery of Manassantin A Protein Targets Using Large-Scale Protein Folding and Stability Measurements." Journal of proteome research 15.8 (August 2016): 2688-2696. Full Text

Geer, MA, and Fitzgerald, MC. "Characterization of the Saccharomyces cerevisiae ATP-Interactome using the iTRAQ-SPROX Technique." Journal of the American Society for Mass Spectrometry 27.2 (February 2016): 233-243. Full Text

Kwon, D-Y, Lee, HE, Weitzel, DH, Park, K, Lee, SH, Lee, C-T, Stephenson, TN, Park, H, Fitzgerald, MC, Chi, J-T, Mook, RA, Dewhirst, MW, Lee, YM, and Hong, J. "Synthesis and Biological Evaluation of Manassantin Analogues for Hypoxia-Inducible Factor 1α Inhibition." Journal of medicinal chemistry 58.19 (October 2015): 7659-7671. Full Text

Adhikari, J, West, GM, and Fitzgerald, MC. "Global analysis of protein folding thermodynamics for disease state characterization." Journal of proteome research 14.5 (May 2015): 2287-2297. Full Text

Adhikari, J, and Fitzgerald, MC. "SILAC-pulse proteolysis: A mass spectrometry-based method for discovery and cross-validation in proteome-wide studies of ligand binding." Journal of the American Society for Mass Spectrometry 25.12 (December 2014): 2073-2083. Full Text