Faculty Profiles

Kenichi Yokoyama
Assistant Professor of Biochemistry
Office: 
307 Research Drive, Rm 233A Nanaline H Duke Bldg, Durham, NC 27710
Phone: 
(919) 684-8848

Overview

Education:

Ph.D., Tokyo Institute of Technology 2008

Ravichandran, K, Minnihan, EC, Lin, Q, Yokoyama, K, Taguchi, AT, Shao, J, Nocera, DG, and Stubbe, J. "Glutamate 350 Plays an Essential Role in Conformational Gating of Long-Range Radical Transport in Escherichia coli Class Ia Ribonucleotide Reductase." Biochemistry (February 2, 2017). Full Text

Hover, BM, Lilla, EA, and Yokoyama, K. "Mechanistic Investigation of cPMP Synthase in Molybdenum Cofactor Biosynthesis Using an Uncleavable Substrate Analogue." Biochemistry 54.49 (December 2015): 7229-7236. Full Text

Yokoyama, K, and Leimkühler, S. "The role of FeS clusters for molybdenum cofactor biosynthesis and molybdoenzymes in bacteria." Biochimica et biophysica acta 1853.6 (June 2015): 1335-1349. (Review) Full Text

Hover, BM, Tonthat, NK, Schumacher, MA, and Yokoyama, K. "Mechanism of pyranopterin ring formation in molybdenum cofactor biosynthesis." Proceedings of the National Academy of Sciences of the United States of America 112.20 (May 4, 2015): 6347-6352. Full Text

Hover, BM, and Yokoyama, K. "C-Terminal glycine-gated radical initiation by GTP 3',8-cyclase in the molybdenum cofactor biosynthesis." Journal of the American Chemical Society 137.9 (March 2, 2015): 3352-3359. Full Text

Wei, Y, Mathies, G, Yokoyama, K, Chen, J, Griffin, RG, and Stubbe, J. "A chemically competent thiosulfuranyl radical on the Escherichia coli class III ribonucleotide reductase." Journal of the American Chemical Society 136.25 (June 17, 2014): 9001-9013. Full Text

Hover, BM, Loksztejn, A, Ribeiro, AA, and Yokoyama, K. "Identification of a cyclic nucleotide as a cryptic intermediate in molybdenum cofactor biosynthesis." J Am Chem Soc 135.18 (May 8, 2013): 7019-7032. Full Text

Wörsdörfer, B, Conner, DA, Yokoyama, K, Livada, J, Seyedsayamdost, M, Jiang, W, Silakov, A, Stubbe, J, Bollinger, JM, and Krebs, C. "Function of the diiron cluster of Escherichia coli class Ia ribonucleotide reductase in proton-coupled electron transfer." Journal of the American Chemical Society 135.23 (2013): 8585-8593. Full Text

Ando, N, Brignole, EJ, Zimanyi, CM, Funk, MA, Yokoyama, K, Asturias, FJ, Stubbe, J, and Drennan, CL. "Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase." Proceedings of the National Academy of Sciences of the United States of America 108.52 (2011): 21046-21051. Full Text

Yokoyama, K, Smith, AA, Corzilius, B, Griffin, RG, and Stubbe, J. "Equilibration of tyrosyl radicals (Y 356·, Y 731·, Y 730·) in the radical propagation pathway of the Escherichia coli class Ia ribonucleotide reductase." Journal of the American Chemical Society 133.45 (2011): 18420-18432. Full Text

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