Faculty Profiles

Katherine J. Franz
Alexander F. Hehmeyer Professor of Chemistry and Department Chair
Office: 
2103 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1541

Overview

Education:

Ph.D., Massachusetts Institute of Technology 2000

B.A., Wellesley College 1995

Research Areas:
Biomolecular Structure and Function, Inorganic

Franks, AT, Wang, Q, and Franz, KJ. "A multifunctional, light-activated prochelator inhibits UVA-induced oxidative stress." Bioorganic & Medicinal Chemistry Letters 25.21 (November 2015): 4843-4847. Full Text

Pushie, MJ, Shaw, K, Franz, KJ, Shearer, J, and Haas, KL. "Model Peptide Studies Reveal a Mixed Histidine-Methionine Cu(I) Binding Site at the N-Terminus of Human Copper Transporter 1." Inorganic Chemistry 54.17 (September 2015): 8544-8551. Full Text

Alies, B, Wiener, JD, and Franz, KJ. "A prochelator peptide designed to use heterometallic cooperativity to enhance metal ion affinity." Chemical Science 6.6 (June 2015): 3606-3610. Full Text

Crumbliss, AL, Franz, KJ, and Thiele, DJ. "Preface." BioMetals 28.3 (June 2015): 431-431. Full Text

Crumbliss, AL, Franz, KJ, and Thiele, DJ. "Preface. Biometals 2014--Proceedings of the 9th International Symposium Biometals 2014 at Duke University, Durham, NC, USA." Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine 28.3 (June 2015): 431-null. Full Text

Helsel, ME, and Franz, KJ. "Pharmacological activity of metal binding agents that alter copper bioavailability." Dalton Transactions (Cambridge, England : 2003) 44.19 (May 2015): 8760-8770. Full Text

Bureš, J, Jansová, H, Stariat, J, Filipský, T, Mladěnka, P, Šimůnek, T, Kučera, R, Klimeš, J, Wang, Q, Franz, KJ, and Kovaříková, P. "LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH)." Journal of Pharmaceutical and Biomedical Analysis 105 (February 2015): 55-63. Full Text

Franks, AT, Wang, Q, and Franz, KJ. "A multifunctional, light-activated prochelator inhibits UVA-induced oxidative stress." Bioorganic and Medicinal Chemistry Letters 25.21 (2015): 4843-4847. Full Text

Franks, AT, and Franz, KJ. "A prochelator with a modular masking group featuring hydrogen peroxide activation with concurrent fluorescent reporting." Chemical communications (Cambridge, England) 50.77 (October 2014): 11317-11320. Full Text

Safi, R, Nelson, ER, Chitneni, SK, Franz, KJ, George, DJ, Zalutsky, MR, and McDonnell, DP. "Copper signaling axis as a target for prostate cancer therapeutics." Cancer Research 74.20 (October 2014): 5819-5831. Full Text Open Access Copy

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