Ph.D., Massachusetts Institute of Technology 2000
B.A., Wellesley College 1995
Pushie, MJ, Shaw, K, Franz, KJ, Shearer, J, and Haas, KL. "Model Peptide Studies Reveal a Mixed Histidine-Methionine Cu(I) Binding Site at the N-Terminus of Human Copper Transporter 1." Inorganic chemistry 54.17 (September 2015): 8544-8551. Full Text
Alies, B, Wiener, JD, and Franz, KJ. "A prochelator peptide designed to use heterometallic cooperativity to enhance metal ion affinity." Chemical science 6.6 (June 2015): 3606-3610. Full Text
Crumbliss, AL, Franz, KJ, and Thiele, DJ. "Preface. Biometals 2014--Proceedings of the 9th International Symposium Biometals 2014 at Duke University, Durham, NC, USA." Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 28.3 (June 2015): 431-. Full Text
Helsel, ME, and Franz, KJ. "Pharmacological activity of metal binding agents that alter copper bioavailability." Dalton transactions (Cambridge, England : 2003) 44.19 (May 2015): 8760-8770. Full Text
Bureš, J, Jansová, H, Stariat, J, Filipský, T, Mladěnka, P, Šimůnek, T, Kučera, R, Klimeš, J, Wang, Q, Franz, KJ, and Kovaříková, P. "LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH)." Journal of pharmaceutical and biomedical analysis 105 (February 2015): 55-63. Full Text
Franks, AT, Wang, Q, and Franz, KJ. "A multifunctional, light-activated prochelator inhibits UVA-induced oxidative stress." Bioorganic and Medicinal Chemistry Letters 25.21 (2015): 4843-4847. Full Text
Franks, AT, and Franz, KJ. "A prochelator with a modular masking group featuring hydrogen peroxide activation with concurrent fluorescent reporting." Chemical communications (Cambridge, England) 50.77 (October 2014): 11317-11320. Full Text
Safi, R, Nelson, ER, Chitneni, SK, Franz, KJ, George, DJ, Zalutsky, MR, and McDonnell, DP. "Copper signaling axis as a target for prostate cancer therapeutics." Cancer research 74.20 (October 2014): 5819-5831. Full Text Open Access Copy
Jansová, H, Macháček, M, Wang, Q, Hašková, P, Jirkovská, A, Potůčková, E, Kielar, F, Franz, KJ, and Simůnek, T. "Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury." Free radical biology & medicine 74 (September 2014): 210-221. Full Text
Rubino, JT, and Franz, KJ. "Characterization of thioether-only Cu(I) binding by Ctr1 methionine motifs." August 16, 2009.
Dickens, MG, Daniel, CL, Pham, DM, and Franz, KJ. "Synthesis of masked bidentate and hexadentate iron chelators designed to reduce oxidative stress." August 16, 2009.
Haas, KL, White, DR, and Franz, KJ. "Spectroscopic studies of N-terminal Cu(II)- and Cu(I)-binding hCtrl model peptides." August 16, 2009.
Franz, KJ. "Design of triggerable ligands for altering metal coordination in biological settings." August 16, 2009.
Ciesienski, KL, Haas, KL, Dickens, MG, and Franz, KJ. "Photolabile ligand for light-activated release of caged copper." March 22, 2009.
Hunt, LM, and Franz, KJ. "INOR 273-Development of prochelators as probes of iron-induced oxidative stress." April 6, 2008.
Crider, SE, and Franz, KJ. "INOR 277-Interactions of cisplatin and methionine-rich peptide domains of the human high-affinity copper transporter Ctr1." April 6, 2008.
Franz, KJ, and Charkoudian, LK. "INOR 916-A pro-chelator strategy for inhibiting metal-catalyzed oxidative stress." August 19, 2007.
Franz, KJ, Haas, K, Rubino, J, and Pham, D. "INOR 1011-Copper(I) binding by methionine-rich domains of copper transport proteins." September 10, 2006.
Charkoudian, LK, and Franz, KJ. "INOR 614-Development of iron chelators triggered by reactive oxygen species." September 10, 2006.