Faculty Profiles

Katherine J. Franz
Alexander F. Hehmeyer Professor of Chemistry
Office: 
2103 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1541

Overview

Education:

Ph.D., Massachusetts Institute of Technology 2000

B.A., Wellesley College 1995

Research Areas:
Biomolecular Structure and Function, Inorganic

Crumbliss, AL, Franz, KJ, and Thiele, DJ. "Preface. Biometals 2014--Proceedings of the 9th International Symposium Biometals 2014 at Duke University, Durham, NC, USA." Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 28.3 (June 2015): 431-. Full Text

Helsel, ME, and Franz, KJ. "Pharmacological activity of metal binding agents that alter copper bioavailability." Dalton transactions (Cambridge, England : 2003) 44.19 (May 2015): 8760-8770. Full Text

Bureš, J, Jansová, H, Stariat, J, Filipský, T, Mladěnka, P, Šimůnek, T, Kučera, R, Klimeš, J, Wang, Q, Franz, KJ, and Kovaříková, P. "LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH)." Journal of pharmaceutical and biomedical analysis 105 (February 2015): 55-63. Full Text

Alies, B, Wiener, JD, and Franz, KJ. "A prochelator peptide designed to use heterometallic cooperativity to enhance metal ion affinity." Chem. Sci. 6.6 (2015): 3606-3610. Full Text

Franks, AT, Wang, Q, and Franz, KJ. "A multifunctional, light-activated prochelator inhibits UVA-induced oxidative stress." Bioorganic and Medicinal Chemistry Letters 25.21 (2015): 4843-4847. Full Text

Safi, R, Nelson, ER, Chitneni, SK, Franz, KJ, George, DJ, Zalutsky, MR, and McDonnell, DP. "Copper signaling axis as a target for prostate cancer therapeutics." Cancer research 74.20 (October 2014): 5819-5831. Full Text Open Access Copy

Franks, AT, and Franz, KJ. "A prochelator with a modular masking group featuring hydrogen peroxide activation with concurrent fluorescent reporting." Chemical communications (Cambridge, England) 50.77 (October 2014): 11317-11320. Full Text

Jansová, H, Macháček, M, Wang, Q, Hašková, P, Jirkovská, A, Potůčková, E, Kielar, F, Franz, KJ, and Simůnek, T. "Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury." Free radical biology & medicine 74 (September 2014): 210-221. Full Text

Festa, RA, Helsel, ME, Franz, KJ, and Thiele, DJ. "Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection." Chemistry & biology 21.8 (August 2014): 977-987. Full Text

Festa, RA, Helsel, ME, Franz, KJ, and Thiele, DJ. "Innate immune cell activation of a copper-dependent anti-cryptococcal agent." MYCOSES 57 (May 2014): 56-57.

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