Faculty Profiles

Katherine J. Franz
Alexander F. Hehmeyer Professor of Chemistry
Office: 
2103 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1541

Overview

Education:

Ph.D., Massachusetts Institute of Technology 2000

B.A., Wellesley College 1995

Research Areas:
Biomolecular Structure and Function, Inorganic

Charkoudian, LK, Dentchev, T, Lukinova, N, Wolkow, N, Dunaief, JL, and Franz, KJ. "Iron prochelator BSIH protects retinal pigment epithelial cells against cell death induced by hydrogen peroxide." J Inorg Biochem 102.12 (December 2008): 2130-2135. Full Text

Ciesienski, KL, Haas, KL, Dickens, MG, Tesema, YT, and Franz, KJ. "A photolabile ligand for light-activated release of caged copper." J Am Chem Soc 130.37 (September 17, 2008): 12246-12247. Full Text

Tesema, YT, Pham, DM, and Franz, KJ. "Counterions influence reactivity of metal ions with cysteinyldopa model compounds." Inorg Chem 47.3 (February 4, 2008): 1087-1095. Full Text

Franz, KJ. "Copper shares a piece of the π." Nature Chemical Biology 4.2 (2008): 85-86. Full Text

Charkoudian, LK, Pham, DM, Kwon, AM, Vangeloff, AD, and Franz, KJ. "Modifications of boronic ester pro-chelators triggered by hydrogen peroxide tune reactivity to inhibit metal-promoted oxidative stress." Dalton Trans 43 (November 21, 2007): 5031-5042. Full Text

Liu, LL, and Franz, KJ. "Phosphorylation-dependent metal binding by alpha-synuclein peptide fragments." J Biol Inorg Chem 12.2 (February 2007): 234-247. Full Text

Charkoudian, LK, Pham, DM, and Franz, KJ. "A pro-chelator triggered by hydrogen peroxide inhibits iron-promoted hydroxyl radical formation." J Am Chem Soc 128.38 (September 27, 2006): 12424-12425. Full Text

Jiang, J, Nadas, IA, Kim, MA, and Franz, KJ. "A Mets motif peptide found in copper transport proteins selectively binds Cu(I) with methionine-only coordination." Inorg Chem 44.26 (December 26, 2005): 9787-9794. Full Text

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