Faculty Profiles

Jiyong Hong
Professor of Chemistry
Office: 
3220 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1545
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., The Scripps Research Institute 2001

M.S., Seoul National University 1995

B.S., Seoul National University 1993

Research Areas:
Synthesis, Biological, Organic

Kim, H, Kasper, AC, Moon, EJ, Park, Y, Wooten, CM, Dewhirst, MW, and Hong, J. "Nucleophilic Addition of Organozinc Reagents to 2-Sulfonyl Cyclic Ethers: Stereoselective Synthesis of Manassantins A and B (Org. Lett., (2009) 11:7 (1671-1671)." Organic Letters 11.7 (2009): 1671--. Full Text

Ying, Y, Liu, Y, Byeon, SR, Kim, H, Luesch, H, and Hong, J. "Synthesis and activity of largazole analogues with linker and macrocycle modification." Org Lett 10.18 (September 18, 2008): 4021-4024. Full Text

Ying, Y, Taori, K, Kim, H, Hong, J, and Luesch, H. "Total synthesis and molecular target of largazole, a histone deacetylase inhibitor." J Am Chem Soc 130.26 (July 2, 2008): 8455-8459. Full Text

Lee, H, Kim, KW, Park, J, Kim, H, Kim, S, Kim, D, Hu, X, Yang, W, and Hong, J. "A general strategy for construction of both 2,6-cis- and 2,6-trans-disubstituted tetrahydropyrans: Substrate-controlled asymmetric total synthesis of (+)-scanlonenyne." Angewandte Chemie - International Edition 47.22 (2008): 4200-4203. Full Text

Lee, J, Wu, X, Magliano, MPD, Peters, EC, Wang, Y, Hong, J, Hebrok, M, Ding, S, Cho, CY, and Schultz, PG. "A small-molecule antagonist of the Hedgehog signaling pathway." ChemBioChem 8.16 (2007): 1916-1919. Full Text

Hong, J, Lee, J, Min, KH, Walker, JR, Peters, EC, Gray, NS, Cho, CY, and Schultz, PG. "Identification and characterization of small-molecule inducers of epidermal keratinocyte differentiation." ACS Chemical Biology 2.3 (2007): 171-175. Full Text

Collins, CS, Hong, J, Sapinoso, L, Zhou, Y, Liu, Z, Micklash, K, Schultz, PG, and Hampton, GM. "A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase." Proceedings of the National Academy of Sciences of the United States of America 103.10 (2006): 3775-3780. Full Text

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