Faculty Profiles

Jiyong Hong
Professor of Chemistry
Office: 
3220 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1545
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., The Scripps Research Institute 2001

M.S., Seoul National University 1995

B.S., Seoul National University 1993

Research Areas:
Synthesis, Biological, Organic

Lee, S-U, Kwak, HB, Pi, S-H, You, H-K, Byeon, SR, Ying, Y, Luesch, H, Hong, J, and Kim, SH. "In vitro and in vivo osteogenic activity of largazole." ACS Medicinal Chemistry Letters 2.3 (2011): 248-251. Full Text

Kim, H, Baker, JB, Park, Y, Park, H-B, DeArmond, PD, Kim, SH, Fitzgerald, MC, Lee, D-S, and Hong, J. "Total synthesis, assignment of the absolute stereochemistry, and structure-activity relationship studies of subglutinols A and B." Chem Asian J 5.8 (August 2, 2010): 1902-1910. Full Text

Liu, Y, Salvador, LA, Byeon, S, Ying, Y, Kwan, JC, Law, BK, Hong, J, and Luesch, H. "Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor." Journal of Pharmacology and Experimental Therapeutics 335.2 (2010): 351-361. Full Text

Yuan, L, Seo, J-S, Kang, NS, Keinan, S, Steele, SE, Michelotti, GA, Wetsel, WC, Beratan, DN, Gong, Y-D, Lee, TH, and Hong, J. "Identification of 3-hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-ones as isoform-selective PKC-zeta inhibitors and potential therapeutics for psychostimulant abuse." Molecular Biosystems 5.9 (September 2009): 927-930. Full Text

Kasper, AC, Moon, EJ, Hu, X, Park, Y, Wooten, CM, Kim, H, Yang, W, Dewhirst, MW, and Hong, J. "Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurations." Bioorg Med Chem Lett 19.14 (July 15, 2009): 3783-3786. Full Text

Kasper, AC, Baker, JB, Kim, H, and Hong, J. "The end game of chemical genetics: target identification." Future Med Chem 1.4 (July 2009): 727-736. (Review) Full Text

Kim, H, Baker, JB, Lee, S-U, Park, Y, Bolduc, KL, Park, H-B, Dickens, MG, Lee, D-S, Kim, Y, Kim, SH, and Hong, J. "Stereoselective synthesis and osteogenic activity of subglutinols A and B." J Am Chem Soc 131.9 (March 11, 2009): 3192-3194. Full Text

Lee, J, Hong, J, Nam, T-G, Peters, EC, Orth, AP, Geierstanger, BH, Goldfinger, LE, Ginsberg, MH, Cho, CY, and Schultz, PG. "A small molecule inhibitor of alpha4 integrin-dependent cell migration." Bioorganic & Medicinal Chemistry 17.3 (February 2009): 977-980. Full Text

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