Faculty Profiles

Jiyong Hong
Professor of Chemistry
Office: 
3220 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1545
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., The Scripps Research Institute 2001

M.S., Seoul National University 1995

B.S., Seoul National University 1993

Research Areas:
Synthesis, Biological, Organic

Yu, M, Salvador, LA, Sy, SKB, Tang, Y, Singh, RSP, Chen, Q-Y, Liu, Y, Hong, J, Derendorf, H, and Luesch, H. "Largazole pharmacokinetics in rats by LC-MS/MS." Marine drugs 12.3 (March 20, 2014): 1623-1640. Full Text

Strickland, EC, Geer, MA, Hong, J, and Fitzgerald, MC. "False-positive rate determination of protein target discovery using a covalent modification- and mass spectrometry-based proteomics platform." J Am Soc Mass Spectrom 25.1 (January 2014): 132-140. Full Text

Chung, BC, Zhao, J, Gillespie, RA, Kwon, D-Y, Guan, Z, Hong, J, Zhou, P, and Lee, S-Y. "Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis." Science 341.6149 (August 30, 2013): 1012-1016. Full Text

Law, ME, Corsino, PE, Jahn, SC, Davis, BJ, Chen, S, Patel, B, Pham, K, Lu, J, Sheppard, B, Nørgaard, P, Hong, J, Higgins, P, Kim, J-S, Luesch, H, and Law, BK. "Glucocorticoids and histone deacetylase inhibitors cooperate to block the invasiveness of basal-like breast cancer cells through novel mechanisms." Oncogene 32.10 (2013): 1316-1329. Full Text

Chung, BC, Zhao, J, Gillespie, RA, Kwon, D-Y, Guan, Z, Hong, J, Zhou, P, and Lee, S-Y. "Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis." Science 341.6149 (2013): 1012-1016. Full Text

Lee, K, Kim, H, and Hong, J. "N-Heterocyclic carbene catalyzed oxidative macrolactonization: total synthesis of (+)-dactylolide." Angew Chem Int Ed Engl 51.23 (June 4, 2012): 5735-5738. Full Text

Hong, J, and Luesch, H. "Largazole: from discovery to broad-spectrum therapy." Nat Prod Rep 29.4 (April 2012): 449-456. (Review) Full Text

Kaoud, TS, Yan, C, Mitra, S, Tseng, C-C, Jose, J, Taliaferro, JM, Tuohetahuntila, M, Devkota, A, Sammons, R, Park, J, Park, H, Shi, Y, Hong, J, Ren, P, and Dalby, KN. "From in silico discovery to intracellular activity: Targeting JNK-protein interactions with small molecules." ACS Medicinal Chemistry Letters 3.9 (2012): 721-725. Full Text

Lee, W-G, Kim, W-S, Park, S-G, Kim, H, Hong, J, Ko, H, and Kim, Y-C. "Immunosuppressive Effects of Subglutinol Derivatives." ChemMedChem 7.2 (2012): 218-222. Full Text

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