Faculty Profiles

Jiyong Hong
Professor of Chemistry
Office: 
3220 French Science Center, 124 Science Drive, Durham, NC 27708
Phone: 
(919) 660-1545
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., The Scripps Research Institute 2001

M.S., Seoul National University 1995

B.S., Seoul National University 1993

Research Areas:
Synthesis, Biological, Organic

Lim, W, Park, J, Lee, YH, Hong, J, and Lee, Y. "Subglutinol A, an immunosuppressive α-pyrone diterpenoid from Fusarium subglutinans, acts as an estrogen receptor antagonist." Biochemical and biophysical research communications 461.3 (June 2015): 507-512. Full Text

Kim, B, and Hong, J. "An overview of naturally occurring histone deacetylase inhibitors." Current topics in medicinal chemistry 14.24 (January 2015): 2759-2782. (Review) Full Text

Kim, B, Park, H, Salvador, LA, Serrano, PE, Kwan, JC, Zeller, SL, Chen, QY, Ryu, S, Liu, Y, Byeon, S, Luesch, H, and Hong, J. "Evaluation of class i HDAC isoform selectivity of largazole analogues." Bioorganic and Medicinal Chemistry Letters 24.16 (August 15, 2014): 3728-3731. Full Text

Hong, J. "Natural product synthesis at the interface of chemistry and biology." Chemistry (Weinheim an der Bergstrasse, Germany) 20.33 (August 2014): 10204-10212. Full Text

Kim, B, Park, H, Salvador, LA, Serrano, PE, Kwan, JC, Zeller, SL, Chen, Q-Y, Ryu, S, Liu, Y, Byeon, S, Luesch, H, and Hong, J. "Evaluation of class I HDAC isoform selectivity of largazole analogues." Bioorganic & medicinal chemistry letters 24.16 (August 2014): 3728-3731. Full Text

Salvador, LA, Park, H, Al-Awadhi, FH, Liu, Y, Kim, B, Zeller, SL, Chen, Q-Y, Hong, J, and Luesch, H. "Modulation of Activity Profiles for Largazole-Based HDAC Inhibitors through Alteration of Prodrug Properties." ACS Medicinal Chemistry Letters 5.8 (August 2014): 905-910. Full Text

Johnson, ZL, Lee, J-H, Lee, K, Lee, M, Kwon, D-Y, Hong, J, and Lee, S-Y. "Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters." ELIFE 3 (July 31, 2014). Full Text

Johnson, ZL, Lee, J-H, Lee, K, Lee, M, Kwon, D-Y, Hong, J, and Lee, S-Y. "Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters." eLife 3 (July 31, 2014): e03604-. Full Text

Lanier, ML, Kasper, AC, Kim, H, and Hong, J. "Synthesis of α,α'-trans-oxepanes through an organocatalytic oxa-conjugate addition reaction." Organic letters 16.9 (May 2014): 2406-2409. Full Text

Lin, R, Kim, H, Hong, J, and Li, Q-J. "Biological evaluation of subglutinol a as a novel immunosuppressive agent for inflammation intervention." ACS medicinal chemistry letters 5.5 (May 2014): 485-490. Full Text

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