Faculty Profiles

Hashim Al-Hashimi
James B. Duke Professor of Biochemistry

Overview

Education:

Ph.D., Yale University 2000

Bothe, JR, Stein, ZW, and Al-Hashimi, HM. "Evaluating the uncertainty in exchange parameters determined from off-resonance R1ρ relaxation dispersion for systems in fast exchange." Journal of magnetic resonance (San Diego, Calif. : 1997) 244 (July 2014): 18-29. Full Text

Zeng, X, Chugh, J, Casiano-Negroni, A, Al-Hashimi, HM, and Brooks, CL. "Flipping of the Ribosomal A-Site Adenines Provides a Basis for tRNA Selection (Accepted)." Journal of Molecular Biology (June 10, 2014). Full Text

Eichhorn, CD, and Al-Hashimi, HM. "Structural dynamics of a single-stranded RNA-helix junction using NMR." RNA 20.6 (June 2014): 782-791. Full Text

Yang, S, Salmon, L, and Al-Hashimi, HM. "Measuring similarity between dynamic ensembles of biomolecules." Nature methods 11.5 (May 2014): 552-554. Full Text

Mustoe, AM, Al-Hashimi, HM, and Brooks, CL. "Coarse grained models reveal essential contributions of topological constraints to the conformational free energy of RNA bulges." The journal of physical chemistry. B 118.10 (March 3, 2014): 2615-2627. Full Text

Kimsey, I, and Al-Hashimi, HM. "Increasing occurrences and functional roles for high energy purine-pyrimidine base-pairs in nucleic acids." Current opinion in structural biology 24 (February 2014): 72-80. (Review) Full Text

Mustoe, AM, Brooks, CL, and Al-Hashimi, HM. "Hierarchy of RNA functional dynamics." Annual review of biochemistry 83 (January 2014): 441-466. (Review) Full Text

Salmon, L, Yang, S, and Al-Hashimi, HM. "Advances in the determination of nucleic acid conformational ensembles." Annual review of physical chemistry 65 (January 2014): 293-316. (Review) Full Text

Suddala, KC, Rinaldi, AJ, Feng, J, Mustoe, AM, Eichhorn, CD, Liberman, JA, Wedekind, JE, Al-Hashimi, HM, Brooks, CL, and Walter, NG. "Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure." Nucleic acids research 41.22 (December 2013): 10462-10475. Full Text

Nikolova, EN, Zhou, H, Gottardo, FL, Alvey, HS, Kimsey, IJ, and Al-Hashimi, HM. "A historical account of Hoogsteen base-pairs in duplex DNA." Biopolymers 99.12 (December 2013): 955-968. Full Text

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