Faculty Profiles

Hashim Al-Hashimi
James B. Duke Professor of Biochemistry

Overview

Education:

Ph.D., Yale University 2000

Yang, S, Salmon, L, and Al-Hashimi, HM. "Measuring similarity between dynamic ensembles of biomolecules." Nature methods 11.5 (May 2014): 552-554. Full Text

Mustoe, AM, Al-Hashimi, HM, and Brooks, CL. "Coarse grained models reveal essential contributions of topological constraints to the conformational free energy of RNA bulges." The journal of physical chemistry. B 118.10 (March 3, 2014): 2615-2627. Full Text

Kimsey, I, and Al-Hashimi, HM. "Increasing occurrences and functional roles for high energy purine-pyrimidine base-pairs in nucleic acids." Current opinion in structural biology 24 (February 2014): 72-80. (Review) Full Text

Mustoe, AM, Brooks, CL, and Al-Hashimi, HM. "Hierarchy of RNA functional dynamics." Annual review of biochemistry 83 (January 2014): 441-466. (Review) Full Text

Salmon, L, Yang, S, and Al-Hashimi, HM. "Advances in the determination of nucleic acid conformational ensembles." Annual review of physical chemistry 65 (January 2014): 293-316. (Review) Full Text

Nikolova, EN, Zhou, H, Gottardo, FL, Alvey, HS, Kimsey, IJ, and Al-Hashimi, HM. "A historical account of Hoogsteen base-pairs in duplex DNA." Biopolymers 99.12 (December 2013): 955-968. Full Text

Al-Hashimi, HM. "NMR studies of nucleic acid dynamics." Journal of magnetic resonance (San Diego, Calif. : 1997) 237 (December 2013): 191-204. Full Text

Suddala, KC, Rinaldi, AJ, Feng, J, Mustoe, AM, Eichhorn, CD, Liberman, JA, Wedekind, JE, Al-Hashimi, HM, Brooks, CL, and Walter, NG. "Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure." Nucleic acids research 41.22 (December 2013): 10462-10475. Full Text

Horowitz, S, Dirk, LMA, Yesselman, JD, Nimtz, JS, Adhikari, U, Mehl, RA, Scheiner, S, Houtz, RL, Al-Hashimi, HM, and Trievel, RC. "Conservation and functional importance of carbon-oxygen hydrogen bonding in AdoMet-dependent methyltransferases." Journal of the American Chemical Society 135.41 (October 7, 2013): 15536-15548. Full Text

Lee, J, Vogt, CE, McBrairty, M, and Al-Hashimi, HM. "Influence of dimethylsulfoxide on RNA structure and ligand binding." Analytical chemistry 85.20 (October 2013): 9692-9698. Full Text

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