Faculty Profiles

Eric John Toone
Professor of Chemistry
Office: 
215 Morris Street, Suite 300, Durham, NC 27708
Phone: 
(919) 681-3484
Fax: 
(919) 660-1591

Overview

Education:

Ph.D., University of Toronto (Canada) 1988

M.S., University of Toronto (Canada) 1985

B.S., University of Guelph (Canada) 1983

Research Areas:
Synthesis, Physical, Organic

Wymer, N, Buchanan, LV, Henderson, D, Mehta, N, Botting, CH, Pocivavsek, L, Fierke, CA, Toone, EJ, and Naismith, JH. "Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli." Structure 9.1 (January 10, 2001): 1-9.

Ditusa, CA, Fierke, CA, and Toone, EJ. "Thermodynamics of Metal Ion Bonding. II. Metal Ion Binding by Mutated Carbonic Anhydrases." Biochemistry 40.18 (2001): 5345-5351. (Academic Article)

Trzaska, SM, Toone, EJ, and Crumbliss, AL. "Microcalorimetric determination of thermodynamic parameters for ionophore-siderophore host-guest complex formation." Inorg Chem 39.6 (March 20, 2000): 1071-1075.

Wymer, N, and Toone, EJ. "Enzyme-catalyzed synthesis of carbohydrates." Curr Opin Chem Biol 4.1 (February 2000): 110-119. (Review)

Debenham, SD, and Toone, EJ. "Regioselective reduction of 4,6-O-benzylidenes using triethylsilane and BF3.Et2O." Tetrahedron Asymmetry 11.2 (2000): 385-387. Full Text

Corbell, JB, Lundquist, JJ, and Toone, EJ. "A comparison of biological and calorimetric analyses of multivalent glycodendrimer ligands for concanavalin A." Tetrahedron Asymmetry 11.1 (2000): 95-111. Full Text

Debenham, S, and Toone, EJ. "A Facile Method for the Reductive Deprotection of Carbohydrate Benzylidene Protecting Groups." Tetrahedron Asymm. (2000): 385-387. (Academic Article)

Corbell, JB, Lundquist, JJ, and Toone, EJ. "Biological and Calorimetric Analysis of Multivalent Glycodendrimers Ligands for Concanavalin A." Tetrahedron Asymm. 11 (2000): 95-111. (Academic Article)

Lundquist, JJ, Debenham, SD, and Toone, EJ. "Calorimetric and Biological Evaluation of Shigalike Toxin1 Binding to Multivalent C-Linked Glycopeptides." J. Org. Chem. 65 (2000): 8245-8250. (Academic Article)

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