Faculty Profiles

Eric John Toone
Professor of Chemistry
Office: 
215 Morris Street, Suite 300, Durham, NC 27708
Phone: 
(919) 681-3484
Fax: 
(919) 660-1591

Overview

Education:

Ph.D., University of Toronto (Canada) 1988

M.S., University of Toronto (Canada) 1985

B.S., University of Guelph (Canada) 1983

Research Areas:
Synthesis, Physical, Organic

Perry, JL, Christensen, T, Goldsmith, MR, Toone, EJ, Beratan, DN, and Simon, JD. "Binding of ochratoxin a to human serum albumin stabilized by a protein-ligand ion pair." Journal of Physical Chemistry B 107.31 (2003): 7884-7888.

Stamler, JS, and Toone, EJ. "The decomposition of thionitrites." Curr Opin Chem Biol 6.6 (December 2002): 779-785. (Review)

Griffiths, JS, Wymer, NJ, Njolito, E, Niranjanakumari, S, Fierke, CA, and Toone, EJ. "Cloning, isolation and characterization of the Thermotoga maritima KDPG aldolase." Bioorg Med Chem 10.3 (March 2002): 545-550.

Lundquist, JJ, and Toone, EJ. "The cluster glycoside effect." Chem Rev 102.2 (February 2002): 555-578. (Review)

Lundquist, JJ, Kiburz, BM, Wu, JK, Jr, KDG, and Toone, EJ. "Towards high affinity carbohydrate-binding proteins: Directed evolution of murine galectin-3." Canadian Journal of Chemistry 80.8 (2002): 999-1009. Full Text

Choi, BY, Voyksner, RD, and Toone, EJ. "Analysis of S-nitrosothiol decomposition." Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics (2002): 799-800.

Bartberger, MD, Mannion, JD, Powell, SC, Stamler, JS, Houk, KN, and Toone, EJ. "S-N dissociation energies of S-nitrosothiols: on the origins of nitrosothiol decomposition rates." J Am Chem Soc 123.36 (September 12, 2001): 8868-8869.

DiTusa, CA, Christensen, T, McCall, KA, Fierke, CA, and Toone, EJ. "Thermodynamics of metal ion binding. 1. Metal ion binding by wild-type carbonic anhydrase." Biochemistry 40.18 (May 8, 2001): 5338-5344.

Moya, MP, Gow, AJ, McMahon, TJ, Toone, EJ, Cheifetz, IM, Goldberg, RN, and Stamler, JS. "S-nitrosothiol repletion by an inhaled gas regulates pulmonary function." Proc Natl Acad Sci U S A 98.10 (May 8, 2001): 5792-5797. Full Text

DiTusa, CA, McCall, KA, Christensen, T, Mahapatro, M, Fierke, CA, and Toone, EJ. "Thermodynamics of metal ion binding. 2. Metal ion binding by carbonic anhydrase variants." Biochemistry 40.18 (May 8, 2001): 5345-5351.

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