Faculty Profiles

Eric John Toone
Professor of Chemistry
215 Morris Street, Suite 300, Durham, NC 27708
(919) 681-3484
(919) 660-1591



Ph.D., University of Toronto (Canada) 1988

M.S., University of Toronto (Canada) 1985

B.S., University of Guelph (Canada) 1983

Research Areas:
Synthesis, Physical, Organic

Winter-Vann, AM, Baron, RA, Wong, W, dela Cruz, J, York, JD, Gooden, DM, Bergo, MO, Young, SG, Toone, EJ, and Casey, PJ. "A small-molecule inhibitor of isoprenylcysteine carboxyl methyltransferase with antitumor activity in cancer cells." Proc Natl Acad Sci U S A 102.12 (March 22, 2005): 4336-4341. Full Text

Mori, T, Hatano, K, Matsuoka, K, Esumi, Y, Toone, EJ, and Terunuma, D. "Synthesis of carbosilane dendrimers having peripheral mannose and mannobiose." Tetrahedron 61.11 (2005): 2751-2760. Full Text

Gooden, DM, Chakrapani, H, and Toone, EJ. "C-nitroso compounds: synthesis, physicochemical properties and biological activities." Curr Top Med Chem 5.7 (2005): 687-705. (Review)

Snyder, PW, Lee, G, Marszalke, PE, Clark, RL, and Toone, EJ. "Quantitative determination of analytes by force microscopy (Submitted)." J. Am. Chem. Soc. (2005). (Academic Article)

Pamula, VK, Srinivasan, V, Chakrapani, H, Fair, RB, and Toone, EJ. "A droplet-based lab-on-a-chip for colorimetric detection of nitroaromatic explosives." Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) (2005): 722-725. Full Text

Griffiths, JS, Cheriyan, M, Corbell, JB, Pocivavsek, L, Fierke, CA, and Toone, EJ. "A bacterial selection for the directed evolution of pyruvate aldolases." Bioorg Med Chem 12.15 (August 1, 2004): 4067-4074. Full Text

Debenham, SD, Snyder, PW, and Toone, EJ. "Solid-phase synthesis for the identification of high-affinity bivalent lectin ligands." J Org Chem 68.15 (July 25, 2003): 5805-5811. Full Text

Christensen, T, Gooden, DM, Kung, JE, and Toone, EJ. "Additivity and the physical basis of multivalency effects: a thermodynamic investigation of the calcium EDTA interaction." J Am Chem Soc 125.24 (June 18, 2003): 7357-7366. Full Text

Houk, KN, Hietbrink, BN, Bartberger, MD, McCarren, PR, Choi, BY, Voyksner, RD, Stamler, JS, and Toone, EJ. "Nitroxyl disulfides, novel intermediates in transnitrosation reactions." J Am Chem Soc 125.23 (June 11, 2003): 6972-6976. Full Text

Perry, JL, Christensen, T, Goldsmith, MR, Toone, EJ, Beratan, DN, and Simon, JD. "Binding of ochratoxin a to human serum albumin stabilized by a protein-ligand ion pair." Journal of Physical Chemistry B 107.31 (2003): 7884-7888.