Faculty Profiles

Dewey G. McCafferty
Professor of Chemistry
B120 LSRC, Box 90346, 450 Research Drive, Dept. Chemistry, Durham, NC 27708-0346
(919) 660-1516
(919) 660-1605



Ph.D., University of North Carolina at Chapel Hill 1995

B.S., North Carolina State University 1990

Research Areas:
Synthesis, Biomolecular Structure and Function, Biological, Organic

McCafferty, DG, Cudic, P, Frankel, BA, Barkallah, S, Kruger, RG, and Li, W. "Chemistry and biology of the ramoplanin family of peptide antibiotics." Biopolymers - Peptide Science Section 66.4 (2002): 261-284. Full Text

Cudic, P, Kranz, JK, Behenna, DC, Kruger, RG, Tadesse, H, Wand, AJ, Veklich, YI, Weisel, JW, and McCafferty, DG. "Complexation of peptidoglycan intermediates by the lipoglycodepsipeptide antibiotic ramoplanin: Minimal structural requirements for intermolecular complexation and fibril formation." Proceedings of the National Academy of Sciences of the United States of America 99.11 (2002): 7384-7389. Full Text

Cudic, P, Behenna, DC, Yu, MK, Kruger, RG, Szewczuk, LM, and McCafferty, DG. "Synthesis of P1-Citronellyl-P2-α-D-pyranosyl pyrophosphates as potential substrates for the E. coli undecaprenyl-pyrophosphoryl-N-acetylglucoseaminyl transferase MurG." Bioorganic and Medicinal Chemistry Letters 11.24 (2001): 3107-3110. Full Text

McCafferty, DG, Cudic, P, Yu, MK, Behenna, DC, and Kruger, R. "Synergy and duality in peptide antibiotic mechanisms." Current Opinion in Chemical Biology 3.6 (1999): 672-680. Full Text

McCafferty, DG, Friesen, DA, Danielson, E, Wall, CG, Saderholm, MJ, Erickson, BW, and Meyer, TJ. "Photochemical energy conversion in a helical oligoproline assembly." Proceedings of the National Academy of Sciences of the United States of America 93.16 (1996): 8200-8204. Full Text

McCafferty, DG, Slate, CA, Nakhle, BM, Jr, HDG, Austell, TL, Vachet, RW, Mullis, BH, and Erickson, BW. "Engineering of a 129-residue tripod protein by chemoselective ligation of proline-II helices." Tetrahedron 51.36 (1995): 9859-9872. Full Text

McCafferty, DG, Bishop, BM, Wall, CG, Hughes, SG, Mecklenberg, SL, Meyer, TJ, and Erickson, BW. "Synthesis of redox derivatives of lysine and their use in solid-phase synthesis of a light-harvesting peptide." Tetrahedron 51.4 (1995): 1093-1106.