Faculty Profiles

Barbara Ramsay R. Shaw
William T. Miller Professor Emeritus of Chemistry
Office: 
1105 French Family Science Ctr, Box 90346, Chemistry Department, Durham, NC 27708-0346
Phone: 
(919) 451-9197
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., University of Washington 1973

M.S., University of Washington 1967

B.A., Bryn Mawr College 1965

Hall, AHS, Wan, J, Shaughnessy, EE, Ramsay Shaw, B, and Alexander, KA. "RNA interference using boranophosphate siRNAs: structure-activity relationships." Nucleic Acids Research 32.20 (January 2004): 5991-6000. Full Text

Shaw, BR, Dobrikov, M, Wang, X, Wan, J, He, K, Lin, J-L, Li, P, Rait, V, Sergueeva, ZA, and Sergueev, D. "Reading, writing, and modulating genetic information with boranophosphate mimics of nucleotides, DNA, and RNA." Annals of the New York Academy of Sciences 1002 (December 2003): 12-29. Full Text

Li, P, and Shaw, BR. "One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate." Nucleosides Nucleotides Nucleic Acids 22.5-8 (May 2003): 699-701. Full Text

Wang, X, Dobrikov, M, Sergueev, D, and Shaw, BR. "RNase H activation by stereoregular boranophosphate oligonucleotide." Nucleosides Nucleotides Nucleic Acids 22.5-8 (May 2003): 1151-1153. Full Text

Dobrikov, MI, Sergueeva, ZA, and Shaw, BR. "Incorporation of (alpha-P-borano)-2',3'-dideoxycytidine 5'-triphosphate into DNA by drug-resistant MMLV reverse transcriptase and Taq DNA polymerase." Nucleosides Nucleotides Nucleic Acids 22.5-8 (May 2003): 1651-1655. Full Text

Li, P, and Shaw, BR. "Synthesis of nucleoside 3',5'-cyclic boranophosphorothioate, a new type of cyclic nucleotide." Chem Commun (Camb) 23 (December 7, 2002): 2890-2891.

Fisher, AA, Ye, DJ, Sergueev, DS, Fisher, MH, Shaw, BR, and Juliano, RL. "Evaluating the specificity of antisense oligonucleotide conjugates - A DNA array analysis." JOURNAL OF BIOLOGICAL CHEMISTRY 277.25 (June 21, 2002): 22980-22984. Full Text

Li, P, and Shaw, BR. "Synthesis of prodrug candidates: conjugates of amino acid with nucleoside boranophosphate." Org Lett 4.12 (June 13, 2002): 2009-2012.

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