Faculty Profiles

Barbara R. Shaw
William T. Miller Professor Emeritus of Chemistry
Office: 
1105 French Family Science Ctr, Box 90346, Chemistry Department, Durham, NC 27708-0346
Phone: 
(919) 660-1551
Fax: 
(919) 660-1605

Overview

Education:

Ph.D., University of Washington 1973

M.S., University of Washington 1967

B.A., Bryn Mawr College 1965

Hall, AHS, Wan, J, Shaughnessy, EE, Shaw, BR, and Alexander, KA. "RNA interference using boranophosphate siRNAs: structure-activity relationships." NUCLEIC ACIDS RESEARCH 32.20 (2004): 5991-6000. Full Text

Shaw, BR, Dobrikov, M, Wang, X, Wan, J, He, K, Lin, J-L, Li, P, Rait, V, Sergueeva, ZA, and Sergueev, D. "Reading, writing, and modulating genetic information with boranophosphate mimics of nucleotides, DNA, and RNA." Ann N Y Acad Sci 1002 (December 2003): 12-29.

Li, P, and Shaw, BR. "One-pot synthesis of an AZT boranophosphate conjugated with tyrosine: a potential prodrug candidate." Nucleosides Nucleotides Nucleic Acids 22.5-8 (May 2003): 699-701. Full Text

Wang, X, Dobrikov, M, Sergueev, D, and Shaw, BR. "RNase H activation by stereoregular boranophosphate oligonucleotide." Nucleosides Nucleotides Nucleic Acids 22.5-8 (May 2003): 1151-1153. Full Text

Dobrikov, MI, Sergueeva, ZA, and Shaw, BR. "Incorporation of (alpha-P-borano)-2',3'-dideoxycytidine 5'-triphosphate into DNA by drug-resistant MMLV reverse transcriptase and Taq DNA polymerase." Nucleosides Nucleotides Nucleic Acids 22.5-8 (May 2003): 1651-1655. Full Text

Li, P, and Shaw, BR. "Synthesis of nucleoside 3',5'-cyclic boranophosphorothioate, a new type of cyclic nucleotide." Chem Commun (Camb) 23 (December 7, 2002): 2890-2891.

Fisher, AA, Ye, DJ, Sergueev, DS, Fisher, MH, Shaw, BR, and Juliano, RL. "Evaluating the specificity of antisense oligonucleotide conjugates - A DNA array analysis." JOURNAL OF BIOLOGICAL CHEMISTRY 277.25 (June 21, 2002): 22980-22984. Full Text

Li, P, and Shaw, BR. "Synthesis of prodrug candidates: conjugates of amino acid with nucleoside boranophosphate." Org Lett 4.12 (June 13, 2002): 2009-2012.

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