Faculty Profiles

Ashutosh Chilkoti
Alan L. Kaganov Professor of Biomedical Engineering
Office: 
1427 CIEMAS, Durham, NC 27708
Phone: 
(919) 660-5373
Fax: 
+1 919 660 5409

Overview

Education:

Ph.D., University of Washington 1991

Christensen, T, Hassouneh, W, Trabbic-Carlson, K, and Chilkoti, A. "Predicting transition temperatures of elastin-like polypeptide fusion proteins." Biomacromolecules 14.5 (May 13, 2013): 1514-1519. Full Text

Bellucci, JJ, Amiram, M, Bhattacharyya, J, McCafferty, D, and Chilkoti, A. "Three-in-one chromatography-free purification, tag removal, and site-specific modification of recombinant fusion proteins using sortase A and elastin-like polypeptides." Angew Chem Int Ed Engl 52.13 (March 25, 2013): 3703-3708. Full Text

Amiram, M, Luginbuhl, KM, Li, X, Feinglos, MN, and Chilkoti, A. "Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control." Proc Natl Acad Sci U S A 110.8 (February 19, 2013): 2792-2797. Full Text

McDaniel, JR, Bhattacharyya, J, Vargo, KB, Hassouneh, W, Hammer, DA, and Chilkoti, A. "Self-assembly of thermally responsive nanoparticles of a genetically encoded peptide polymer by drug conjugation." Angew Chem Int Ed Engl 52.6 (February 4, 2013): 1683-1687. Full Text

Tjong, V, Yu, H, Hucknall, A, and Chilkoti, A. "Direct fluorescence detection of RNA on microarrays by surface-initiated enzymatic polymerization." Anal Chem 85.1 (January 2, 2013): 426-433. Full Text

MacEwan, SR, and Chilkoti, A. "Harnessing the power of cell-penetrating peptides: activatable carriers for targeting systemic delivery of cancer therapeutics and imaging agents." Wiley Interdiscip Rev Nanomed Nanobiotechnol 5.1 (January 2013): 31-48. (Review) Full Text

Thapa, A, Han, W, Simons, RH, Chilkoti, A, Chi, EY, and López, GP. "Effect of detergents on the thermal behavior of elastin-like polypeptides." Biopolymers 99.1 (January 2013): 55-62. Full Text

Weller, D, McDaniel, JR, Fischer, K, Chilkoti, A, and Schmidt, M. "Cylindrical polymer brushes with elastin-like polypeptide side chains." Macromolecules 46.12 (2013): 4966-4971. Full Text

Qi, Y, Amiram, M, Gao, W, McCafferty, DG, and Chilkoti, A. "Sortase-Catalyzed Initiator Attachment Enables High Yield Growth of a Stealth Polymer from the C Terminus of a Protein." Macromolecular Rapid Communications 34.15 (2013): 1256-1260. Full Text

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