Faculty Profiles

Ashutosh Chilkoti
Alan L. Kaganov Professor of Biomedical Engineering
Office: 
CIEMAS 3381, Durham, NC 27708
Phone: 
(919) 660-5373
Fax: 
+1 919 660 5409

Overview

Education:

Ph.D., University of Washington 1991

Qi, Y, Amiram, M, Gao, W, McCafferty, DG, and Chilkoti, A. "Sortase-catalyzed initiator attachment enables high yield growth of a stealth polymer from the C terminus of a protein." Macromol Rapid Commun 34.15 (August 2013): 1256-1260. Full Text

Kurzbach, D, Hassouneh, W, McDaniel, JR, Jaumann, EA, Chilkoti, A, and Hinderberger, D. "Hydration layer coupling and cooperativity in phase behavior of stimulus responsive peptide polymers." J Am Chem Soc 135.30 (July 31, 2013): 11299-11308. Full Text

Hassouneh, W, Nunalee, ML, Shelton, MC, and Chilkoti, A. "Calcium binding peptide motifs from calmodulin confer divalent ion selectivity to elastin-like polypeptides." Biomacromolecules 14.7 (July 8, 2013): 2347-2353. Full Text

Christensen, T, Hassouneh, W, Trabbic-Carlson, K, and Chilkoti, A. "Predicting transition temperatures of elastin-like polypeptide fusion proteins." Biomacromolecules 14.5 (May 13, 2013): 1514-1519. Full Text

Bellucci, JJ, Amiram, M, Bhattacharyya, J, McCafferty, D, and Chilkoti, A. "Three-in-one chromatography-free purification, tag removal, and site-specific modification of recombinant fusion proteins using sortase A and elastin-like polypeptides." Angew Chem Int Ed Engl 52.13 (March 25, 2013): 3703-3708. Full Text

Amiram, M, Luginbuhl, KM, Li, X, Feinglos, MN, and Chilkoti, A. "Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control." Proc Natl Acad Sci U S A 110.8 (February 19, 2013): 2792-2797. Full Text

McDaniel, JR, Bhattacharyya, J, Vargo, KB, Hassouneh, W, Hammer, DA, and Chilkoti, A. "Self-assembly of thermally responsive nanoparticles of a genetically encoded peptide polymer by drug conjugation." Angew Chem Int Ed Engl 52.6 (February 4, 2013): 1683-1687. Full Text

Tjong, V, Yu, H, Hucknall, A, and Chilkoti, A. "Direct fluorescence detection of RNA on microarrays by surface-initiated enzymatic polymerization." Anal Chem 85.1 (January 2, 2013): 426-433. Full Text

MacEwan, SR, and Chilkoti, A. "Harnessing the power of cell-penetrating peptides: activatable carriers for targeting systemic delivery of cancer therapeutics and imaging agents." Wiley Interdiscip Rev Nanomed Nanobiotechnol 5.1 (January 2013): 31-48. (Review) Full Text

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