Faculty Profiles

Ashutosh Chilkoti
Alan L. Kaganov Professor of Biomedical Engineering
Office: 
CIEMAS 3381, Durham, NC 27708
Phone: 
(919) 660-5373
Fax: 
+1 919 660 5409

Overview

Education:

Ph.D., University of Washington 1991

Sinclair, SM, Bhattacharyya, J, McDaniel, JR, Gooden, DM, Gopalaswamy, R, Chilkoti, A, and Setton, LA. "A genetically engineered thermally responsive sustained release curcumin depot to treat neuroinflammation." J Control Release 171.1 (October 10, 2013): 38-47. Full Text Open Access Copy

McDaniel, JR, Dewhirst, MW, and Chilkoti, A. "Actively targeting solid tumours with thermoresponsive drug delivery systems that respond to mild hyperthermia." Int J Hyperthermia 29.6 (September 2013): 501-510. (Review) Full Text

Khan, MN, Tjong, V, Chilkoti, A, and Zharnikov, M. "Spectroscopic study of a DNA brush synthesized in situ by surface initiated enzymatic polymerization." J Phys Chem B 117.34 (August 29, 2013): 9929-9938. Full Text

McDaniel, JR, Radford, DC, and Chilkoti, A. "A unified model for de novo design of elastin-like polypeptides with tunable inverse transition temperatures." Biomacromolecules 14.8 (August 12, 2013): 2866-2872. Full Text

Qi, Y, Amiram, M, Gao, W, McCafferty, DG, and Chilkoti, A. "Sortase-catalyzed initiator attachment enables high yield growth of a stealth polymer from the C terminus of a protein." Macromol Rapid Commun 34.15 (August 2013): 1256-1260. Full Text

Kurzbach, D, Hassouneh, W, McDaniel, JR, Jaumann, EA, Chilkoti, A, and Hinderberger, D. "Hydration layer coupling and cooperativity in phase behavior of stimulus responsive peptide polymers." J Am Chem Soc 135.30 (July 31, 2013): 11299-11308. Full Text

Hassouneh, W, Nunalee, ML, Shelton, MC, and Chilkoti, A. "Calcium binding peptide motifs from calmodulin confer divalent ion selectivity to elastin-like polypeptides." Biomacromolecules 14.7 (July 8, 2013): 2347-2353. Full Text

Christensen, T, Hassouneh, W, Trabbic-Carlson, K, and Chilkoti, A. "Predicting transition temperatures of elastin-like polypeptide fusion proteins." Biomacromolecules 14.5 (May 13, 2013): 1514-1519. Full Text

Bellucci, JJ, Amiram, M, Bhattacharyya, J, McCafferty, D, and Chilkoti, A. "Three-in-one chromatography-free purification, tag removal, and site-specific modification of recombinant fusion proteins using sortase A and elastin-like polypeptides." Angew Chem Int Ed Engl 52.13 (March 25, 2013): 3703-3708. Full Text

Amiram, M, Luginbuhl, KM, Li, X, Feinglos, MN, and Chilkoti, A. "Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control." Proc Natl Acad Sci U S A 110.8 (February 19, 2013): 2792-2797. Full Text

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