Faculty Profiles

Ashutosh Chilkoti
Alan L. Kaganov Professor of Biomedical Engineering
1427 CIEMAS, Durham, NC 27708
(919) 660-5373
+1 919 660 5409



Ph.D., University of Washington 1991

Amiram, M, Luginbuhl, KM, Li, X, Feinglos, MN, and Chilkoti, A. "A depot-forming glucagon-like peptide-1 fusion protein reduces blood glucose for five days with a single injection." J Control Release 172.1 (November 28, 2013): 144-151. Full Text

Sinclair, SM, Bhattacharyya, J, McDaniel, JR, Gooden, DM, Gopalaswamy, R, Chilkoti, A, and Setton, LA. "A genetically engineered thermally responsive sustained release curcumin depot to treat neuroinflammation." J Control Release 171.1 (October 10, 2013): 38-47. Full Text Open Access Copy

McDaniel, JR, Dewhirst, MW, and Chilkoti, A. "Actively targeting solid tumours with thermoresponsive drug delivery systems that respond to mild hyperthermia." Int J Hyperthermia 29.6 (September 2013): 501-510. (Review) Full Text

Khan, MN, Tjong, V, Chilkoti, A, and Zharnikov, M. "Spectroscopic study of a DNA brush synthesized in situ by surface initiated enzymatic polymerization." J Phys Chem B 117.34 (August 29, 2013): 9929-9938. Full Text

McDaniel, JR, Radford, DC, and Chilkoti, A. "A unified model for de novo design of elastin-like polypeptides with tunable inverse transition temperatures." Biomacromolecules 14.8 (August 12, 2013): 2866-2872. Full Text

Qi, Y, Amiram, M, Gao, W, McCafferty, DG, and Chilkoti, A. "Sortase-catalyzed initiator attachment enables high yield growth of a stealth polymer from the C terminus of a protein." Macromol Rapid Commun 34.15 (August 2013): 1256-1260. Full Text

Kurzbach, D, Hassouneh, W, McDaniel, JR, Jaumann, EA, Chilkoti, A, and Hinderberger, D. "Hydration layer coupling and cooperativity in phase behavior of stimulus responsive peptide polymers." J Am Chem Soc 135.30 (July 31, 2013): 11299-11308. Full Text

Hassouneh, W, Nunalee, ML, Shelton, MC, and Chilkoti, A. "Calcium binding peptide motifs from calmodulin confer divalent ion selectivity to elastin-like polypeptides." Biomacromolecules 14.7 (July 8, 2013): 2347-2353. Full Text

Christensen, T, Hassouneh, W, Trabbic-Carlson, K, and Chilkoti, A. "Predicting transition temperatures of elastin-like polypeptide fusion proteins." Biomacromolecules 14.5 (May 13, 2013): 1514-1519. Full Text

Bellucci, JJ, Amiram, M, Bhattacharyya, J, McCafferty, D, and Chilkoti, A. "Three-in-one chromatography-free purification, tag removal, and site-specific modification of recombinant fusion proteins using sortase A and elastin-like polypeptides." Angew Chem Int Ed Engl 52.13 (March 25, 2013): 3703-3708. Full Text